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Yuhchyau Chen, M.D., Ph.D.

Radiation Oncology , Cancer

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UR Medicine Faculty

Accountable Health Partner

Accepting New Patients

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Appointment (585) 275-2171

Fax (585) 275-1531

Yuhchyau Chen, M.D., Ph.D.

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Locations
About Me
Credentials
Research
Publications
Ratings & Comments

Locations

Wilmot Cancer Center - Rochester

Strong Memorial Hospital
90 Crittenden Boulevard
Rochester, NY 14642

(585) 275-5830 Get Directions

Wilmot Cancer Institute - Webster

875 Hard Road
Webster, NY 14580

(585) 602-3150 Get Directions

About Me

Faculty Appointments

Professor - Department of Radiation Oncology (SMD)

Chair - Department of Radiation Oncology (SMD)

Richard T. Bell Endowed Professorship in Radiation Oncology - Department of Radiation Oncology (SMD)

Credentials

Residency & Fellowship

Fellowship, Harvard Medical School. 1992 - 1995

Residency, Radiation Oncology, Massachusetts General Hospital. 1991 - 1995

Residency, Radiation Oncology, Radiation Oncology Harvard-Massachusetts General Hospital. 1991 - 1995

Internship, Virginia Mason Medical Center. 1990 - 1992

Education

MD | University of Washington School of Medicine. 1990

Awards

Fellow (FASTRO). 2021

Fellow (FAAWR). 2021

Richard T. Bell Endowed Professorship in Radiation Oncology. 2013

Educator of the Year. 2013 - 2014

Philip Rubin Professorship in Radiation Oncology. 2012 - 2013

Fellow. 2012 - 2013

Patient and Family Centered Care Award. 2011 - 2012

Educator of the Year. 2001 - 2002

Buswell Fellowship Award. 1997 - 1998

George Casarett Research Excellence Award. 1995 - 1996

Clinical Oncology Fellowship. 1993 - 1994

Course Honors. 1986 - 1990

Graduate School Research Assistantship. 1983 - 1984

Research Assistantship in Surgery. 1982 - 1983

Research

Clinical Trials

Randomized Phase II/III Trial of Surgery and Postoperative Radiation Delivered With Concurrent Cisplatin Versus Docetaxel Versus Docetaxel and Cetuximab for High-Risk Squamous Cell Cancer of the Head and Neck

Lead Researcher: Yuhchyau Chen

This phase II/III trial studies how well radiation therapy works when given together with cisplatin, docetaxel, cetuximab, and/or atezolizumab after surgery in treating patients with high-risk stage III-IV head and neck cancer the begins in the thin,...

Integration of Immunotherapy Into Adjuvant Therapy for Resected NSCLC: ALCHEMIST Chemo-IO (ACCIO)

Lead Researcher: Yuhchyau Chen

This phase III ALCHEMIST trial tests the addition of pembrolizumab to usual chemotherapy for the treatment of stage IIA, IIB, IIIA or IIIB non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as ...

Publications

Journal Articles

KDM3B Single-Nucleotide Polymorphisms Impact Radiation Therapy Toxicity Through Circular RNA-Mediated KDM3B Expression and Inflammatory Responses

Sun Y; Tsai Y; Wood R; Shen B; Chen J; Zhou Z; Zeng G; Marples B; Kerns S; Chen Y.

Int J Radiat Oncol Biol Phys. 2024; 119(1): 251-260.

KDM3B Single-Nucleotide Polymorphisms Impact Radiation Therapy Toxicity Through Circular RNA-Mediated KDM3B Expression and Inflammatory Responses

Sun Y; Tsai Y; Wood R; Shen B; Chen J; Zhou Z; Zeng G; Marples B; Kerns S; Chen Y.

Int J Radiat Oncol Biol Phys. 2024; 119(1): 251-260.

Body composition and mortality in men receiving prostate radiotherapy: A pooled analysis of NRG/RTOG 9406 and NRG/RTOG 0126.

McDonald AM, DeMora L, Yang ES, Hoyle JM, Lenzie A, Williams GR, Michalski JM, Yee D, Bahary JP, Den RB, Roach M, Dess R, Mishra MV, Valicenti RK, Lau HY, Marcrom SR, Souhami L, Mendez LC, Chen Y, Doncals DE, Pugh SL, Feng FY, Sandler HM

Cancer.. 2023 March 1129 (5):685-696. Epub 12/29/2022.

Lack of hydroxyurea-associated mutagenesis in pediatric sickle cell disease patients

Torous DK; Avlasevich S; Bemis JC; Howard T; Ware RE; Fung C; Chen Y; Sahsrabudhe D; MacGregor JT; Dertinger SD.

Environ Mol Mutagen. 2023; 64(3): 167-175.

Assessment of Differences in Academic Rank and Compensation by Gender and Race/Ethnicity Among Academic Radiation Oncologists in the United States.

Raldow AC, Siker ML, Bonner JA, Chen Y, Liu FF, Metz JM, Movsas B, Potters L, Schultz CJ, Wilson E, Wang X, Romero T, Steinberg ML, Jagsi R

Advances in radiation oncology.. 2023 8 (5):101210. Epub 03/10/2023.

Stroke death in patients receiving radiation for head and neck cancer in the modern era.

Hardy SJ, Bandyopadhyay S, Yang H, Williams A, Gudina A, Cummings MA, Zhang H, Singh DP, Chen Y, Mohile NA, Janelsins MC, Milano MT

Frontiers in oncology.. 2023 13 :1111764. Epub 06/15/2023.

Targeting the radiation-induced ARv7-mediated circNHS/miR-512-5p/XRCC5 signaling with Quercetin increases prostate cancer radiosensitivity.

Chen D, Chou FJ, Chen Y, Huang CP, Tian H, Wang Y, Niu Y, You B, Yeh S, Xing N, Chang C

Journal of experimental & clinical cancer research : CR.. 2022 August 341 (1):235. Epub 08/03/2022.

Methodological Comparison of Mapping the Expanded Prostate Cancer Index Composite to EuroQoL-5D-3L Using Cross-Sectional and Longitudinal Data: Secondary Analysis of NRG/RTOG 0415.

Khairnar R, DeMora L, Sandler HM, Lee WR, Villalonga-Olives E, Mullins CD, Palumbo FB, Bruner DW, Shaya FT, Bentzen SM, Shah AB, Malone S, Michalski JM, Dayes IS, Seaward SA, Albert M, Currey AD, Pisansky TM, Chen Y, Horwitz EM, DeNittis AS, Feng F, Mishra MV

JCO clinical cancer informatics.. 2022 June 6 :e2100188. Epub 1900 01 01.

Risk stratification after recurrence of human papillomavirus (HPV)-related and non-HPV-related oropharyngeal cancer: Secondary analysis of NRG Oncology RTOG 0129 and 0522

Bigelow EO; Harris J; Fakhry C; Gillison ML; Nguyen-Tân PF; Rosenthal DI; Frank SJ; Nair SG; Bahig H; Ridge JA; Caudell J; Donaldson C; Clifford BT; Shenouda G; Birrer MJ; Chen Y; Le QT.

Head Neck. 2022; 44(1): 158-167.

Retraction Note: Radiation-induced glucocorticoid receptor promotes CD44?+?prostate cancer stem cell growth through activation of SGK1-Wnt/?-catenin signaling

Chen F; Chen X; Ren Y; Weng G; Keng PC; Chen Y; Lee SO.

J Mol Med (Berl). 2022; 100(1): 149.

Use of angiotensin converting enzyme inhibitors is associated with reduced risk of late bladder toxicity following radiotherapy for prostate cancer

Kerns SL; Amidon Morlang A; Lee SM; Peterson DR; Marples B; Zhang H; Bylund K; Rosenzweig D; Hall W; De Ruyck K; Rosenstein BS; Stock RG; Gómez-Caamaño A; Vega A; Sosa-Fajardo P; Taboada-Valladares B; Aguado-Barrera ME; Parker C; Veldeman L; Fonteyne V; Bultijnck R; Talbot CJ; Symonds RP; Johnson K; Rattay T; Webb A; Lambrecht M; de Ruysscher D; Vanneste B; Choudhury A; Elliott RM; Sperk E; Herskind C; Veldwijk MR; Rancati T; Avuzzi B; Valdagni R; Azria D; Farcy Jacquet MP...Chen Y; et al.

Radiother Oncol. 2022; 168: 75-82.

Increased risk of high-grade prostate cancer among testicular cancer survivors

Zhang H; Yang H; Bandyopadhyay S; Milano MT; Fung C; Messing EM; Chen Y.

PLoS One. 2022; 17(2): e0263573.

Retraction notice to "Neuroendocrine differentiation contributes to radioresistance development and metastatic potential increase in non-small cell lung cancer" [Biochim. Biophys. Acta, Mol. Cell Res. Volume 1865, Issue 12, December 2018, Pages 1878-1890].

Zhu R, Yang X, Xue X, Shen M, Chen F, Chen X, Tsai Y, Keng PC, Chen Y, Lee SO, Chen Y

Biochimica et biophysica acta. Molecular cell research.. 2021 October 1868 (11):119097. Epub 08/07/2021.

Retraction notice to "FASN-TGF-?1-PD-L1 axis contributes to the development of resistance to NK cell cytotoxicity of cisplatin-resistant lung cancer cells" [BBA - Molecular and Cell Biology of Lipids 1863/3 (March 2018) 313-322].

Shen M, Tsai Y, Zhu R, Keng PC, Chen Y, Chen Y, Lee SO

Biochimica et biophysica acta. Molecular and cell biology of lipids.. 2021 August 1866 (8):158946. Epub 04/28/2021.

Impact of Diabetes and Insulin Use on Prognosis in Patients With Resected Pancreatic Cancer: An Ancillary Analysis of NRG Oncology RTOG 9704

Bitterman DS; Winter KA; Hong TS; Fuchs CS; Regine WF; Abrams RA; Safran H; Hoffman JP; Benson AB; Kasunic T; Mulcahy M; Strauss JF; DiPetrillo T; Stella PJ; Chen Y; Plastaras JP; Crane CH.

Int J Radiat Oncol Biol Phys. 2021; 109(1): 201-211.

Mapping expanded prostate cancer index composite to EQ5D utilities to inform economic evaluations in prostate cancer: secondary analysis of NRG/RTOG 0415

Khairnar R; Pugh SL; Sandler HM; Lee WR; Villalonga Olives E; Mullins CD; Palumbo FB; Bruner DW; Shaya FT; Bentzen SM; Shah AB; Malone SC; Michalski JM; Dayes IS; Seaward SA; Albert M; Currey AD; Pisansky TM; Chen Y; Horwitz EM; DeNittis AS; Feng FY; Mishra MV.

PLoS One. 2021; 16(4): e0249123.

New dosimetric guidelines for linear Boltzmann transport equations through comparative evaluation of stereotactic body radiation therapy for lung treatment planning

Webster M; Tanny S; Joyce N; Herman A; Chen Y; Milano M; Usuki K; Constine L; Singh D; Yeo I.

J Appl Clin Med Phys. 2021; 22(12): 115-124.

Risk of adverse pathological features for intermediate risk prostate cancer: Clinical implications for definitive radiation therapy.

Zhang H, Doucette C, Yang H, Bandyopadhyay S, Grossman CE, Messing EM, Chen Y

PloS one.. 2021 16 (7):e0253936. Epub 07/15/2021.

Corrigendum to "In vitro-induced M2 type macrophages induces the resistance of prostate cancer cells to cytotoxic action of NK cells"[Exp Cell Res 364 (2018) 113-123].

Xu L, Shen M, Chen X, Yang DR, Tsai Y, Keng PC, Lee SO, Chen Y

Experimental cell research.. 2020 June 1391 (1):112006. Epub 04/21/2020.

Marital Status and Overall Survival in Patients with Resectable Pancreatic Cancer: Results of an Ancillary Analysis of NRG Oncology/RTOG 9704.

Reyngold M, Winter KA, Regine WF, Abrams RA, Safran H, Hoffman JP, Mowat RB, Hayes JP, Kessel IL, DiPetrillo T, Narayan S, Chen Y, Ben-Josef E, Delouya G, Suh JH, Meyer J, Haddock MG, Feldman M, Gaur R, Yost K, Peterson RA, Sherr DL, Moughan J, Crane CH

The oncologist.. 2020 March 25 (3):e477-e483. Epub 12/16/2019.

Human blood PIG-A mutation and micronucleated reticulocyte flow cytometric assays: Method optimization and evaluation of intra- and inter-subject variation

Torous DK; Avlasevich SL; Khattab MG; Baig A; Saubermann LJ; Chen Y; Bemis JC; Lovell DP; Walker VE; MacGregor JT; Dertinger SD.

Environ Mol Mutagen. 2020; 61(8): 807-819.

Targeting the radiation-induced TR4 nuclear receptor-mediated QKI/circZEB1/miR-141-3p/ZEB1 signaling increases prostate cancer radiosensitivity

Chen D; Chou FJ; Chen Y; Tian H; Wang Y; You B; Niu Y; Huang CP; Yeh S; Xing N; Chang C.

Cancer Lett. 2020; 495: 100-111.

[Corrigendum] Increased infiltration of macrophages to radioresistant lung cancer cells contributes to the development of the additional resistance of tumor cells to the cytotoxic effects of NK cells

Shen M; Chen Y; Xu L; Zhu R; Xue X; Tsai Y; Keng PC; Lee SO; Chen Y.

Int J Oncol. 2020; 57(4): 1072-1073.

Tolerance doses for late adverse events after hypofractionated radiotherapy for prostate cancer on trial NRG Oncology/RTOG 0415.

Thor M, Deasy JO, Paulus R, Robert Lee W, Amin MB, Bruner DW, Low DA, Shah AB, Malone SC, Michalski JM, Dayes IS, Seaward SA, Gore EM, Albert M, Pisansky TM, Faria SL, Chen Y, Koontz BF, Swanson GP, Pugh SL, Sandler HM

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.. 2019 June 135 :19-24. Epub 03/05/2019.

NF?B and TNF? as individual key molecules associated with the cisplatin-resistance and radioresistance of lung cancer.

Zhu R, Xue X, Shen M, Tsai Y, Keng PC, Chen Y, Lee SO, Chen Y

Experimental cell research.. 2019 January 1374 (1):181-188. Epub 12/01/2018.

Preclinical study using androgen receptor (AR) degradation enhancer to increase radiotherapy efficacy via targeting radiation-increased AR to better suppress prostate cancer progression

Chou FJ; Chen Y; Chen D; Niu Y; Li G; Keng P; Yeh S; Chang C.

EBioMedicine. 2019; 40: 504-516.

NRG Oncology/RTOG 0438: A Phase I Trial of Highly Conformal Radiation Therapy for Liver Metastases

Dawson LA; Winter KA; Katz AW; Schell MC; Brierley J; Chen Y; Kopek N; Crane CH, Willett CG.

Pract Radiat Oncol. 2019; 9(4): e386-e393.

Prophylactic cranial irradiation vs observation in patients with locally advanced non-small cell lung cancer: a long-term update of the NRG Oncology/RTOG 0214 Phase 3 randomized clinical trial

Sun A; Hu C; Wong SJ; Gore E; Videtic G; Dutta S; Suntharalingam M; Chen Y; Gaspar LE; Choy H.

JAMA Oncol. 2019; 5(6): 847-855.

Quality of Life in Patients With Low-Risk Prostate Cancer Treated With Hypofractionated vs Conventional Radiotherapy: A Phase 3 Randomized Clinical Trial

Bruner DW; Pugh SL; Lee WR; Dignam JJ; Low D; Swanson GP; Shah AB; Malone S; Michalski JM; Dayes IS; Seaward SA; Nguyen PL; Hall WA; Pisansky TM; Chen Y; Sandler HM; Movsas B.

JAMA Oncol. 2019; 5(5): 664-670.

Inoperable pulmonary carcinoid tumors: local control rates with stereotactic body radiotherapy/hypofractionated RT with image-guided radiotherapy

Singh D; Chen Y; Cummings MA; Milano MT.

Clin Lung Cancer. 2019; 20(3): e284-e290.

RETRACTED: Neuroendocrine differentiation contributes to radioresistance development and metastatic potential increase in non-small cell lung cancer.

Zhu R, Yang X, Xue X, Shen M, Chen F, Chen X, Tsai Y, Keng PC, Chen Y, Lee SO, Chen Y

Biochimica et biophysica acta. Molecular cell research.. 2018 December 1865 (12):1878-1890. Epub 09/15/2018.

Radiation biology and oncology in the genomic era.

Kerns S, Chuang KH, Hall W, Werner Z, Chen Y, Ostrer H, West C, Rosenstein B

The British journal of radiology.. 2018 November 91 (1091):20170949. Epub 06/14/2018.

Comparison of Single- and Five-fraction Regimens of Stereotactic Body Radiation Therapy for Peripheral Early-stage Non-small-cell Lung Cancer: A Two-institution Propensity-matched Analysis.

Cummings MA, Ma SJ, Hermann G, Serra L, Syed Y, Malhotra HK, Chen Y, Milano MT, Gomez-Suescun JA, Singh DP, Singh AK

Clinical lung cancer.. 2018 November 19 (6):511-517. Epub 07/30/2018.

Smoking, Sex, and Non-Small Cell Lung Cancer: Steroid Hormone Receptors in Tumor Tissue (S0424).

Cheng TD, Darke AK, Redman MW, Zirpoli GR, Davis W, Payne Ondracek R, Bshara W, Omilian AR, Kratzke R, Reid ME, Molina JR, Kolesar JM, Chen Y, MacRae RM, Moon J, Mack P, Gandara DR, Kelly K, Santella RM, Albain KS, Ambrosone CB

Journal of the National Cancer Institute.. 2018 July 1110 (7):734-742. Epub 1900 01 01.

Increased infiltration of macrophages to radioresistant lung cancer cells contributes to the development of the additional resistance of tumor cells to the cytotoxic effects of NK cells.

Shen M, Chen Y, Xu L, Zhu R, Xue X, Tsai Y, Keng PC, Lee SO, Chen Y

International journal of oncology.. 2018 July 53 (1):317-328. Epub 05/04/2018.

Three- Versus Five-Fraction Regimens of Stereotactic Body Radiotherapy for Peripheral Early-Stage Non-Small-Cell Lung Cancer: A Two-Institution Propensity Score-Matched Analysis.

Ma SJ, Cummings M, Serra LM, Syed YA, Hermann GM, Chen Y, Milano MT, Singh AK, Gomez-Suescun JA, Singh DP

Clinical lung cancer.. 2018 May 19 (3):e297-e302. Epub 11/26/2017.

Adipocytes affect castration-resistant prostate cancer cells to develop the resistance to cytotoxic action of NK cells with alterations of PD-L1/NKG2D ligand levels in tumor cells.

Xu L, Shen M, Chen X, Zhu R, Yang DR, Tsai Y, Keng PC, Chen Y, Lee SO

The Prostate.. 2018 April 78 (5):353-364. Epub 01/12/2018.

In vitro-induced M2 type macrophages induces the resistance of prostate cancer cells to cytotoxic action of NK cells.

Xu L, Shen M, Chen X, Yang DR, Tsai Y, Keng PC, Lee SO, Chen Y

Experimental cell research.. 2018 March 1364 (1):113-123. Epub 02/01/2018.

Inhibition of IL-6-JAK/Stat3 signaling in castration-resistant prostate cancer cells enhances the NK cell-mediated cytotoxicity via alteration of PD-L1/NKG2D ligand levels.

Xu L, Chen X, Shen M, Yang DR, Fang L, Weng G, Tsai Y, Keng PC, Chen Y, Lee SO

Molecular oncology.. 2018 March 12 (3):269-286. Epub 01/24/2018.

FASN-TGF-?1-PD-L1 axis contributes to the development of resistance to NK cell cytotoxicity of cisplatin-resistant lung cancer cells.

Shen M, Tsai Y, Zhu R, Keng PC, Chen Y, Chen Y, Lee SO

Biochimica et biophysica acta. Molecular and cell biology of lipids.. 2018 March 1863 (3):313-322. Epub 01/03/2018.

NRG oncology RTOG 9006: a phase III randomized trial of hyperfractionated radiotherapy (RT) and BCNU versus standard RT and BCNU for malignant glioma patients.

Ali AN, Zhang P, Yung WKA, Chen Y, Movsas B, Urtasun RC, Jones CU, Choi KN, Michalski JM, Fischbach AJ, Markoe AM, Schultz CJ, Penas-Prado M, Garg MK, Hartford AC, Kim HE, Won M, Curran WJ

Journal of neuro-oncology.. 2018 March 137 (1):39-47. Epub 02/05/2018.

Phase 1b/2a Trial of the Superoxide Dismutase Mimetic GC4419 to Reduce Chemoradiotherapy-Induced Oral Mucositis in Patients With Oral Cavity or Oropharyngeal Carcinoma.

Anderson CM, Sonis ST, Lee CM, Adkins D, Allen BG, Sun W, Agarwala SS, Venigalla ML, Chen Y, Zhen W, Mould DR, Holmlund JT, Brill JM, Buatti JM

International journal of radiation oncology, biology, physics.. 2018 February 1100 (2):427-435. Epub 10/16/2017.

Stereotactic Body Radiotherapy for Lung Metastases from Colorectal Cancer: Prognostic Factors for Disease Control and Survival.

Qiu H, Katz AW, Chowdhry AK, Usuki KY, Singh DP, Metcalfe S, Cheruvu P, Chen Y, Okunieff P, Milano MT

American journal of clinical oncology.. 2018 January 41 (1):53-58. Epub 1900 01 01.

Postresection CA19-9 and margin status as predictors of recurrence after adjuvant treatment for pancreatic carcinoma: Analysis of NRG oncology RTOG trial 9704.

Regine WF, Winter K, Abrams RA, Safran H, Kessel IL, Chen Y, Fugazzi JA, Donnelly ED, DiPetrillo TA, Narayan S, Plastaras JP, Gaur R, Delouya G, Suh JH, Meyer JE, Haddock MG, Didolkar MS, Padula GDA, Johnson D, Hoffman JP, Crane CH

Advances in radiation oncology.. 2018 3 (2):154-162. Epub 02/09/2018.

Radiation alters PD-L1/NKG2D ligand levels in lung cancer cells and leads to immune escape from NK cell cytotoxicity via IL-6-MEK/Erk signaling pathway.

Shen MJ, Xu LJ, Yang L, Tsai Y, Keng PC, Chen Y, Lee SO, Chen Y

Oncotarget.. 2017 October 68 (46):80506-80520. Epub 07/12/2017.

Randomized Phase II Study of Preoperative Chemoradiotherapy ± Panitumumab Followed by Consolidation Chemotherapy in Potentially Operable Locally Advanced (Stage IIIa, N2+) Non-Small Cell Lung Cancer: NRG Oncology RTOG 0839.

Edelman MJ, Hu C, Le QT, Donington JS, D'Souza WD, Dicker AP, Loo BW, Gore EM, Videtic GMM, Evans NR, Leach JW, Diehn M, Feigenberg SJ, Chen Y, Paulus R, Bradley JD

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.. 2017 September 12 (9):1413-1420. Epub 06/16/2017.

Enhancing NK cell-mediated cytotoxicity to cisplatin-resistant lung cancer cells via MEK/Erk signaling inhibition.

Yang L, Shen M, Xu LJ, Yang X, Tsai Y, Keng PC, Chen Y, Lee SO

Scientific reports.. 2017 August 117 (1):7958. Epub 08/11/2017.

Simultaneous targeting of ATM and Mcl-1 increases cisplatin sensitivity of cisplatin-resistant non-small cell lung cancer.

Zhang F, Shen M, Yang L, Yang X, Tsai Y, Keng PC, Chen Y, Lee SO, Chen Y

Cancer biology & therapy.. 2017 August 318 (8):606-615. Epub 07/07/2017.

Predictors of Radiation Therapy-Related Gastrointestinal Toxicity From Anal Cancer Dose-Painted Intensity Modulated Radiation Therapy: Secondary Analysis of NRG Oncology RTOG 0529.

Olsen JR, Moughan J, Myerson R, Abitbol A, Doncals DE, Johnson D, Schefter TE, Chen Y, Fisher B, Michalski J, Narayan S, Chang A, Crane CH, Kachnic L

International journal of radiation oncology, biology, physics.. 2017 June 198 (2):400-408. Epub 02/13/2017.

IL-6 Mediates Macrophage Infiltration after Irradiation via Up-regulation of CCL2/CCL5 in Non-small Cell Lung Cancer.

Wang X, Yang X, Tsai Y, Yang L, Chuang KH, Keng PC, Lee SO, Chen Y

Radiation research.. 2017 January 187 (1):50-59. Epub 01/05/2017.

Ensuring sample quality for blood biomarker studies in clinical trials: a multicenter international study for plasma and serum sample preparation

Kong F-M; Zhao L; Wang L; Chen Y; Hu J; Fu X; Bai C; Wang L; Lawrence TS; Anscher MS; Dicker A; Okunieff P.

Transl Lung Cancer Res. 2017; 6: 625-634.

Randomized Phase III Noninferiority Study Comparing Two Radiotherapy Fractionation Schedules in Patients With Low-Risk Prostate Cancer.

Lee WR, Dignam JJ, Amin MB, Bruner DW, Low D, Swanson GP, Shah AB, D'Souza DP, Michalski JM, Dayes IS, Seaward SA, Hall WA, Nguyen PL, Pisansky TM, Faria SL, Chen Y, Koontz BF, Paulus R, Sandler HM

Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2016 July 1034 (20):2325-32. Epub 04/04/2016.

Cisplatin treatment increases stemness through upregulation of hypoxia-inducible factors by interleukin-6 in non-small cell lung cancer.

Zhang F, Duan S, Tsai Y, Keng P, Chen Y, Lee SO, Chen Y

Cancer science.. 2016 June 107 (6):746-54. Epub 05/03/2016.

IL-6 promotes growth and epithelial-mesenchymal transition of CD133+ cells of non-small cell lung cancer.

Lee SO, Yang X, Duan S, Tsai Y, Strojny LR, Keng P, Chen Y

Oncotarget.. 2016 February 97 (6):6626-38. Epub 1900 01 01.

A FASN-TGF-?1-FASN regulatory loop contributes to high EMT/metastatic potential of cisplatin-resistant non-small cell lung cancer

Yang L; Zhang F; Wang X; Tsai Y; Chuang KH; Keng PC; Lee SO; Chen Y.

Oncotarget. 2016; 7(34): 55543-55554.

Phase 3 Randomized Low-Dose Paclitaxel Chemoradiotherapy Study for Locally Advanced Non-Small Cell Lung Cancer.

Lin H, Chen Y, Shi A, Pandya KJ, Yu R, Yuan Y, Li J, Li H, Wang Y, Xia T, Feng L, Ma H, Geng J, Zhu G

Frontiers in oncology.. 2016 6 :260. Epub 12/20/2016.

IL-6 signaling promotes DNA repair and prevents apoptosis in CD133+ stem-like cells of lung cancer after radiation.

Chen Y, Zhang F, Tsai Y, Yang X, Yang L, Duan S, Wang X, Keng P, Lee SO

Radiation oncology.. 2015 November 1410 :227. Epub 11/14/2015.

IL-6 signaling contributes to cisplatin resistance in non-small cell lung cancer via the up-regulation of anti-apoptotic and DNA repair associated molecules.

Duan S, Tsai Y, Keng P, Chen Y, Lee SO, Chen Y

Oncotarget.. 2015 September 296 (29):27651-60. Epub 1900 01 01.

Philip Rubin, MD, FASTRO: Reflections on a Radiation Oncology Pioneer.

Constine LS, Chen Y

International journal of radiation oncology, biology, physics.. 2015 June 192 (2):193-5. Epub 1900 01 01.

Human erythrocyte PIG-A assay: an easily monitored index of gene mutation requiring low volume blood samples.

Dertinger SD, Avlasevich SL, Bemis JC, Chen Y, MacGregor JT

Environmental and molecular mutagenesis.. 2015 May 56 (4):366-77. Epub 11/20/2014.

Is there a subset of patients with recurrent cancer in the vagina who are not candidates for interstitial brachytherapy that can be treated with multichannel vaginal brachytherapy using graphic optimization?

Singh DP, Bylund KC, Matloubieh A, Mazloom A, Gray A, Sidhu R, Barrette L, Chen Y

Journal of contemporary brachytherapy.. 2015 April 7 (2):135-41. Epub 04/28/2015.

Local control rates with five fractions of stereotactic body radiotherapy for primary lung tumors: a single institution experience of 153 consecutive patients

Singh D; Chen Y; Bergsma DP; Usuki KY; Dhakal S; Hare MZ; Joyce N; Smudzin T; Rosenzweig D; Schell MC; Milano MT.

Transl Cancer Res. 2015; 4(4): 332-339.

Local control rates with five-fraction stereotactic body radiotherapy for oligometastatic cancer to the lung.

Singh D, Chen Y, Hare MZ, Usuki KY, Zhang H, Lundquist T, Joyce N, Schell MC, Milano MT

Journal of thoracic disease.. 2014 April 6 (4):369-74. Epub 1900 01 01.

Erk/MAP kinase signaling pathway and neuroendocrine differentiation of non-small-cell lung cancer.

Chen Y, Nowak I, Huang J, Keng PC, Sun H, Xu H, Wei G, Lee SO

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.. 2014 January 9 (1):50-8. Epub 1900 01 01.

A case report of long-term survival of metastatic extraskeletal myxoid chondrosarcoma treated with surgery and hypofractionated radiotherapy

Qiu H; Hare M; Chen Y.

J Radiother Pract. 2014; 13: 493-497.

A phase 1 trial of eltrombopag in patients undergoing stem cell transplantation after total body irradiation.

Liesveld JL, Phillips GL, Becker M, Constine LS, Friedberg J, Andolina JR, Milner LA, Debolt J, Smudzin T, Hyrien O, Erickson-Miller CL, Johnson BM, Dawson KL, Chen Y

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.. 2013 December 19 (12):1745-52. Epub 10/08/2013.

Loss of androgen receptor promotes adipogenesis but suppresses osteogenesis in bone marrow stromal cells.

Huang CK, Lai KP, Luo J, Tsai MY, Kang HY, Chen Y, Lee SO, Chang C

Stem cell research.. 2013 September 11 (2):938-50. Epub 06/10/2013.

Increased chemosensitivity via targeting testicular nuclear receptor 4 (TR4)-Oct4-interleukin 1 receptor antagonist (IL1Ra) axis in prostate cancer CD133+ stem/progenitor cells to battle prostate cancer.

Yang DR, Ding XF, Luo J, Shan YX, Wang R, Lin SJ, Li G, Huang CK, Zhu J, Chen Y, Lee SO, Chang C

The Journal of biological chemistry.. 2013 June 7288 (23):16476-16483. Epub 04/22/2013.

Clinical factors affecting engraftment and transfusion needs in SCT: a single-center retrospective analysis.

Liesveld J, Pawlowski J, Chen R, Hyrien O, Debolt J, Becker M, Phillips G, Chen Y

Bone marrow transplantation.. 2013 May 48 (5):691-7. Epub 10/22/2012.

A Pilot Study (SWOG S0429) of Weekly Cetuximab and Chest Radiotherapy for Poor-Risk Stage III Non-Small Cell Lung Cancer.

Chen Y, Moon J, Pandya KJ, Lau DH, Kelly K, Hirsch FR, Gaspar LE, Redman M, Gandara DR

Frontiers in oncology.. 2013 3 :219. Epub 08/28/2013.

Age and Racial Differences among PSA-Detected (AJCC Stage?T1cN0M0) Prostate Cancer in the U.S.: A Population-Based Study of 70,345 Men.

Zhang H, Messing EM, Travis LB, Hyrien O, Chen R, Milano MT, Chen Y

Frontiers in oncology.. 2013 3 :312. Epub 12/23/2013.

Second primary lung cancer after head and neck squamous cell cancer: population-based study of risk factors.

Milano MT, Peterson CR, Zhang H, Singh DP, Chen Y

Head & neck.. 2012 December 34 (12):1782-8. Epub 02/09/2012.

Definitive radiotherapy for stage I nonsmall cell lung cancer: a population-based study of survival.

Milano MT, Zhang H, Usuki KY, Singh DP, Chen Y

Cancer.. 2012 November 15118 (22):5572-9. Epub 04/27/2012.

Eltrombopag, a thrombopoietin receptor agonist, enhances human umbilical cord blood hematopoietic stem/primitive progenitor cell expansion and promotes multi-lineage hematopoiesis.

Sun H, Tsai Y, Nowak I, Liesveld J, Chen Y

Stem cell research.. 2012 September 9 (2):77-86. Epub 05/14/2012.

Use of eltrombopag, a thrombopoietin receptor agonist, in post-transplantation thrombocytopenia.

Reid R, Bennett JM, Becker M, Chen Y, Milner L, Phillips Ii GL, Liesveld J

American journal of hematology.. 2012 July 87 (7):743-5. Epub 05/10/2012.

Impact of radiotherapy on laryngeal cancer survival: a population-based study of 13,808 US patients.

Zhang H, Travis LB, Chen R, Hyrien O, Milano MT, Newlands SD, Chen Y

Cancer.. 2012 March 1118 (5):1276-87. Epub 07/19/2011.

Randomized phase II study of palifermin for reducing dysphagia in patients receiving concurrent chemoradiotherapy for locally advanced unresectable non-small cell lung cancer.

Schuette W, Krzakowski MJ, Massuti B, Otterson GA, Lizambri R, Wei H, Berger DP, Chen Y

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.. 2012 January 7 (1):157-64. Epub 1900 01 01.

Preclinical and pilot clinical studies of docetaxel chemoradiation for Stage III non-small-cell lung cancer.

Chen Y, Pandya KJ, Hyrien O, Keng PC, Smudzin T, Anderson J, Qazi R, Smith B, Watson TJ, Feins RH, Johnstone DW

International journal of radiation oncology, biology, physics.. 2011 August 180 (5):1358-64. Epub 08/12/2010.

Palifermin reduces severe mucositis in definitive chemoradiotherapy of locally advanced head and neck cancer: a randomized, placebo-controlled study.

Le QT, Kim HE, Schneider CJ, Muraközy G, Skladowski K, Reinisch S, Chen Y, Hickey M, Mo M, Chen MG, Berger D, Lizambri R, Henke M

Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2011 July 1029 (20):2808-14. Epub 06/13/2011.

Comparison of outcomes in patients with stage III versus limited stage IV non-small cell lung cancer.

Cheruvu P, Metcalfe SK, Metcalfe J, Chen Y, Okunieff P, Milano MT

Radiation oncology.. 2011 June 306 :80. Epub 06/30/2011.

Sublethal radiation injury uncovers a functional transition during erythroid maturation.

Peslak SA, Wenger J, Bemis JC, Kingsley PD, Frame JM, Koniski AD, Chen Y, Williams JP, McGrath KE, Dertinger SD, Palis J

Experimental hematology.. 2011 April 39 (4):434-45. Epub 02/01/2011.

Response kinetics of radiation-induced micronucleated reticulocytes in human bone marrow culture.

Sun H, Tsai Y, Nowak I, Dertinger SD, Wu JH, Chen Y

Mutation research.. 2011 January 10718 (1-2):38-43. Epub 11/04/2010.

Impact of toxicity grade and scoring system on the relationship between mean lung dose and risk of radiation pneumonitis in a large cohort of patients with non-small cell lung cancer.

Tucker SL, Jin H, Wei X, Wang S, Martel MK, Komaki R, Liu HH, Mohan R, Chen Y, Cox JD, Liao Z

International journal of radiation oncology, biology, physics.. 2010 July 177 (3):691-8. Epub 10/14/2009.

Split-course palliative radiotherapy for advanced non-small cell lung cancer.

Metcalfe SK, Milano MT, Bylund K, Smudzin T, Rubin P, Chen Y

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.. 2010 February 5 (2):185-90. Epub 1900 01 01.

Validating high-throughput micronucleus analysis of peripheral reticulocytes for radiation biodosimetry: benchmark against dicentric and CBMN assays in a mouse model.

Chen Y, Tsai Y, Nowak I, Wang N, Hyrien O, Wilkins R, Ferrarotto C, Sun H, Dertinger SD

Health physics.. 2010 February 98 (2):218-27. Epub 1900 01 01.

Stereotactic body radiotherapy for treatment of adrenal metastases.

Chawla S, Chen Y, Katz AW, Muhs AG, Philip A, Okunieff P, Milano MT

International journal of radiation oncology, biology, physics.. 2009 September 175 (1):71-5. Epub 02/26/2009.

Acupressure bands are effective in reducing radiation therapy-related nausea.

Roscoe JA, Bushunow P, Jean-Pierre P, Heckler CE, Purnell JQ, Peppone LJ, Chen Y, Ling MN, Morrow GR

Journal of pain and symptom management.. 2009 September 38 (3):381-9. Epub 03/28/2009.

Radiation Therapy Oncology Group translational research program stem cell symposium: incorporating stem cell hypotheses into clinical trials.

Woodward WA, Bristow RG, Clarke MF, Coppes RP, Cristofanilli M, Duda DG, Fike JR, Hambardzumyan D, Hill RP, Jordan CT, Milas L, Pajonk F, Curran WJ, Dicker AP, Chen Y

International journal of radiation oncology, biology, physics.. 2009 August 174 (5):1580-91. Epub 06/17/2009.

Radiotherapy plus chemotherapy with or without surgical resection for stage III non-small-cell lung cancer: a phase III randomised controlled trial.

Albain KS, Swann RS, Rusch VW, Turrisi AT, Shepherd FA, Smith C, Chen Y, Livingston RB, Feins RH, Gandara DR, Fry WA, Darling G, Johnson DH, Green MR, Miller RC, Ley J, Sause WT, Cox JD

Lancet.. 2009 August 1374 (9687):379-86. Epub 07/24/2009.

Dose-volume thresholds and smoking status for the risk of treatment-related pneumonitis in inoperable non-small cell lung cancer treated with definitive radiotherapy.

Jin H, Tucker SL, Liu HH, Wei X, Yom SS, Wang S, Komaki R, Chen Y, Martel MK, Mohan R, Cox JD, Liao Z

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.. 2009 June 91 (3):427-32. Epub 10/18/2008.

Central thoracic lesions treated with hypofractionated stereotactic body radiotherapy.

Milano MT, Chen Y, Katz AW, Philip A, Schell MC, Okunieff P

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.. 2009 June 91 (3):301-6. Epub 03/28/2009.

Reticulocyte and micronucleated reticulocyte responses to gamma irradiation: effect of age.

Dertinger SD, Bemis JC, Phonethepswath S, Tsai Y, Nowak I, Hyrien O, Palis J, Chen Y

Mutation research.. 2009 April 30675 (1-2):77-80. Epub 02/11/2009.

Gamma-radiation induces micronucleated reticulocytes in 3D bone marrow bioreactors in vitro.

Sun H, Dertinger SD, Hyrien O, Wu JH, Chen Y

Mutation research.. 2009 680 (1-2):49-55. Epub 09/26/2009.

Molecular markers of radiation-related normal tissue toxicity.

Okunieff P, Chen Y, Maguire DJ, Huser AK

Cancer metastasis reviews.. 2008 September 27 (3):363-74. Epub 1900 01 01.

Toxicity profile and pharmacokinetic study of a phase I low-dose schedule-dependent radiosensitizing paclitaxel chemoradiation regimen for inoperable non-small-cell lung cancer.

Chen Y, Pandya KJ, Feins R, Johnstone DW, Watson T, Smudzin T, Keng PC

International journal of radiation oncology, biology, physics.. 2008 June 171 (2):407-13. Epub 12/31/2007.

Tumor response kinetics after schedule-dependent paclitaxel chemoradiation treatment for inoperable non-small cell lung cancer: a model for low-dose chemotherapy radiosensitization.

Zhang H, Hyrien O, Pandya KJ, Keng PC, Chen Y

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.. 2008 June 3 (6):563-8. Epub 1900 01 01.

Reticulocyte and micronucleated reticulocyte responses to gamma irradiation: dose-response and time-course profiles measured by flow cytometry.

Dertinger SD, Tsai Y, Nowak I, Hyrien O, Sun H, Bemis JC, Torous DK, Keng P, Palis J, Chen Y

Mutation research.. 2007 December 1634 (1-2):119-25. Epub 07/05/2007.

Open-label, long-term safety study of cevimeline in the treatment of postirradiation xerostomia.

Chambers MS, Jones CU, Biel MA, Weber RS, Hodge KM, Chen Y, Holland JM, Ship JA, Vitti R, Armstrong I, Garden AS, Haddad R

International journal of radiation oncology, biology, physics.. 2007 December 169 (5):1369-76. Epub 09/12/2007.

Automated human blood micronucleated reticulocyte measurements for rapid assessment of chromosomal damage.

Dertinger SD, Miller RK, Brewer K, Smudzin T, Torous DK, Roberts DJ, Avlasevich SL, Bryce SM, Sugunan S, Chen Y

Mutation research.. 2007 January 10626 (1-2):111-9. Epub 10/23/2006.

Adverse event reporting and developments in radiation biology after normal tissue injury: International Atomic Energy Agency consultation.

Chen Y, Trotti A, Coleman CN, Machtay M, Mirimanoff RO, Hay J, O'brien PC, El-Gueddari B, Salvajoli JV, Jeremic B

International journal of radiation oncology, biology, physics.. 2006 April 164 (5):1442-51. Epub 01/18/2006.

Interleukin (IL)-1A and IL-6: applications to the predictive diagnostic testing of radiation pneumonitis.

Chen Y, Hyrien O, Williams J, Okunieff P, Smudzin T, Rubin P

International journal of radiation oncology, biology, physics.. 2005 May 162 (1):260-6. Epub 1900 01 01.

Mechanism and modification of gastrointestinal soft tissue response to radiation: role of growth factors.

Okunieff P, Cornelison T, Mester M, Liu W, Ding I, Chen Y, Zhang H, Williams JP, Finkelstein J

International journal of radiation oncology, biology, physics.. 2005 May 162 (1):273-8. Epub 1900 01 01.

Past, present, and future of oxygen in cancer research.

Okunieff P, Fenton B, Chen Y

Advances in experimental medicine and biology.. 2005 566 :213-22. Epub 1900 01 01.

Radiation and third-generation chemotherapy.

Chen Y, Okunieff P

Hematology/oncology clinics of North America.. 2004 February 18 (1):55-80. Epub 1900 01 01.

Three-color labeling method for flow cytometric measurement of cytogenetic damage in rodent and human blood.

Dertinger SD, Camphausen K, Macgregor JT, Bishop ME, Torous DK, Avlasevich S, Cairns S, Tometsko CR, Menard C, Muanza T, Chen Y, Miller RK, Cederbrant K, Sandelin K, Pontén I, Bolcsfoldi G

Environmental and molecular mutagenesis.. 2004 44 (5):427-35. Epub 1900 01 01.

Micronucleated CD71-positive reticulocytes: a blood-based endpoint of cytogenetic damage in humans.

Dertinger SD, Chen Y, Miller RK, Brewer KJ, Smudzin T, Torous DK, Hall NE, Olvany KA, Murante FG, Tometsko CR

Mutation research.. 2003 December 9542 (1-2):77-87. Epub 1900 01 01.

Combination of radiation and celebrex (celecoxib) reduce mammary and lung tumor growth.

Liu W, Chen Y, Wang W, Keng P, Finkelstein J, Hu D, Liang L, Guo M, Fenton B, Okunieff P, Ding I

American journal of clinical oncology.. 2003 August 26 (4):S103-9. Epub 1900 01 01.

The biological basis of a comprehensive grading system for the adverse effects of cancer treatment.

Williams J, Chen Y, Rubin P, Finkelstein J, Okunieff P

Seminars in radiation oncology.. 2003 July 13 (3):182-8. Epub 1900 01 01.

Phase I/II clinical study of pulsed paclitaxel radiosensitization for thoracic malignancy: a therapeutic approach on the basis of preclinical research of human cancer cell lines.

Chen Y, Pandya K, Keng PC, Johnstone D, Li J, Lee YJ, Smudzin T, Okunieff P

Clinical cancer research : an official journal of the American Association for Cancer Research.. 2003 March 9 (3):969-75. Epub 1900 01 01.

Translational research in lung cancer.

Chen Y, Okunieff P, Ahrendt SA

Seminars in surgical oncology.. 2003 21 (3):205-19. Epub 1900 01 01.

Radiation pneumonitis and early circulatory cytokine markers.

Chen Y, Williams J, Ding I, Hernady E, Liu W, Smudzin T, Finkelstein JN, Rubin P, Okunieff P

Seminars in radiation oncology.. 2002 January 12 (1 Suppl 1):26-33. Epub 1900 01 01.

Predictive value of histologic tumor necrosis after radiation.

Chen Y, Taghian AG, Rosenberg AE, O'Connell J, Okunieff P, Suit HD

International journal of cancer.. 2001 December 2096 (6):334-40. Epub 1900 01 01.

Schedule-dependent pulsed paclitaxel radiosensitization for thoracic malignancy.

Chen Y, Pandya K, Keng PP, Feins R, Raubertas R, Smudzin T, Rosenblatt J, Okunieff P

American journal of clinical oncology.. 2001 October 24 (5):432-7. Epub 1900 01 01.

Circulating IL-6 as a predictor of radiation pneumonitis.

Chen Y, Rubin P, Williams J, Hernady E, Smudzin T, Okunieff P

International journal of radiation oncology, biology, physics.. 2001 March 149 (3):641-8. Epub 1900 01 01.

Circulating basic fibroblast growth factor declines during Cy/TBI bone marrow transplantation.

Okunieff P, Barrett AJ, Phang SE, Li A, Constine LS, Williams JP, Rubin P, Wang X, Wu T, Chen Y, Ding I

Bone marrow transplantation.. 1999 June 23 (11):1117-21. Epub 1900 01 01.

Cell-cycle analysis using continuous bromodeoxyuridine labeling and Hoechst 33358-ethidium bromide bivariate flow cytometry.

Poot M, Hoehn H, Kubbies M, Grossmann A, Chen Y, Rabinovitch PS

Methods in cell biology.. 1994 41 :327-40. Epub 1900 01 01.

In vivo phosphorus NMR spectroscopy of skin using a crossover surface coil.

Chen Y, Richards TL, Izenberg S, Golden RN, Williams DL, Nelson JA, Steen RG

Magnetic resonance in medicine.. 1992 January 23 (1):46-54. Epub 1900 01 01.

Mitogen response and cell cycle kinetics of Swiss 3T3 cells in defined medium: differences from human fibroblasts and effects of cell density.

Chen YY, Rabinovitch PS

Experimental cell research.. 1990 October 190 (2):145-50. Epub 1900 01 01.

Altered cell cycle responses to insulin-like growth factor I, but not platelet-derived growth factor and epidermal growth factor, in senescing human fibroblasts.

Chen YY, Rabinovitch PS

Journal of cellular physiology.. 1990 July 144 (1):18-25. Epub 1900 01 01.

Cell cycle analysis using continuous bromodeoxyuridine labeling and Hoechst 33258-ethidium bromide bivariate flow cytometry.

Poot M, Hoehn H, Kubbies M, Grossmann A, Chen YC, Rabinovitch PS

Methods in cell biology.. 1990 33 :185-98. Epub 1900 01 01.

Platelet-derived growth factor, epidermal growth factor, and insulin-like growth factor I regulate specific cell-cycle parameters of human diploid fibroblasts in serum-free culture.

Chen Y, Rabinovitch PS

Journal of cellular physiology.. 1989 July 140 (1):59-67. Epub 1900 01 01.

Differential proliferation of fibroblasts cultured from normal and fibrotic human lungs.

Raghu G, Chen YY, Rusch V, Rabinovitch PS

The American review of respiratory disease.. 1988 September 138 (3):703-8. Epub 1900 01 01.

BrdU-Hoechst flow cytometry: a unique tool for quantitative cell cycle analysis.

Rabinovitch PS, Kubbies M, Chen YC, Schindler D, Hoehn H

Experimental cell research.. 1988 February 174 (2):309-18. Epub 1900 01 01.

Books

ALERT-Adverse Late Effects of Cancer Treatment (2014)

Chapter: Upper Respiratory and Digestive System: Pharynx, Larynx, and Xerostomia

Advances in Radiation Oncology in Lung Cancer (2011)

Chapter: Translational Research in Lung Cancer

Lung Cancer: Translational & Emerging Therapies (2007)

Chapter: Advances in Chemoradiation Treatment of Locoregionally Advanced Non-small Cell Lung Cancer

Tumors of the Chest: Biology Diagnosis and Management (2006)

Chapter: Molecular Staging of Non-small Cell Lung Cancer

Advances in Radiation Oncology in Lung Cancer. Medical Radiology- Diagnostic Ima (2005)

Chapter: Translational Research in Radiation Oncology of Lung Cancer.

Survivors of Childhood Cancer: Assessment and Management (2005)

Chapter: Pulmonary Effects of Antineoplastic Therapy

Clinical Radiation Oncology: Indications, Techniques, and Results (2000)

Chapter: The Lymphomas.

Current Clinical Oncology: Intraoperative Irradiation-Techniques and Results (1999)

Chapter: Biology of large dose per fraction radiation therapy.

Principles and Practice of Radiation Oncology (1997)

Chapter: Staging and Classification of Cancer: A Unified Approach.

Flow Cytometry: Advanced Research and Clinical Applications (1992)

Chapter: Cell cycle analysis via BrdU-Hoechst flow cytometry: principles and applications

Ratings & Comments

At URMC, we believe that patients should be empowered to make the right decisions regarding their personal healthcare. To do so, transparency is critical. URMC partners with Press Ganey, to survey our patients about all aspects of their care experience. We are now putting this pertinent information at your fingertips by displaying star ratings for our providers along with anonymous patient comments on our website. This will help you make better-informed choices about how and with whom you seek care. Click here to learn more about the surveys used to generate this vital information. Learn more about our survey process.

Ratings

Care provider's discussion of any proposed treatment (options, risks, benefits, etc.)

4.8

Likelihood of recommending this care provider to others

4.8

Explanations the care provider gave you about your problem or condition

4.8

Care provider's efforts to include you in decisions about your care

4.8

Concern the care provider showed for your questions or worries

4.9

Patient Comments

5.0

Dr; Chen ws very clear in explaining the radiatiodn procedures. She also listened carefully to our questions.

Sep 06, 2024

Frankly, I have complete trust in Dr. Chen... And that trust does not come easily.

Feb 22, 2024

5.0

Excellent care for me.

Feb 27, 2023

Dr Chen and her PA are very nice and caring.

Jan 24, 2023

5.0

she is very knowledgeable and professional. I am very pleased with our visit

Oct 24, 2022

5.0

Good

Sep 21, 2022