Skip to content
Find a Provider
John C. Grable, M.D., Ph.D.

John C. Grable, M.D., Ph.D.

Primary Care , Internal Medicine

5 out of 5 stars
131 Ratings
21 Comments
UR Medicine Faculty The University of Rochester Medical Faculty Group (URMFG) consists of over 900 specialist and primary care providers spanning 19 departments. URMFG is certified by the National Committee for Quality Assurance.
Accountable Health Partner Accountable Health Partners (AHP) is a network of over 2,000 community and UR medical faculty and a dozen leading hospitals throughout the region. AHP offers a full range of care.
Not Accepting New Patients

Contact

Appointment (585) 275-5681
Fax (585) 273-1041

Locations

Strong Internal Medicine - Rochester

Ambulatory Care Center at Strong Memorial Hospital
601 Elmwood Avenue, 5th Floor
Rochester, NY 14642

(585) 275-5681 Get Directions

About Me

Dr. Grable is Professor of Medicine at URMC. After serving in the U.S. Army, he received his Ph.D. in Biology and M.D. degree from the University of Pittsburgh. Dr. Grable then completed his Internal Medicine Residency at URMC. His duties include seeing patients as a Hospitalist, as a IM resident cl...
Dr. Grable is Professor of Medicine at URMC. After serving in the U.S. Army, he received his Ph.D. in Biology and M.D. degree from the University of Pittsburgh. Dr. Grable then completed his Internal Medicine Residency at URMC. His duties include seeing patients as a Hospitalist, as a IM resident clinic preceptor and in private practice. He is an Assistant Program Director for the residency program and performs tobacco cessation research.

Faculty Appointments

Professor of Clinical Medicine (Part-Time) - Department of Medicine, General Medicine (SMD)

Credentials

Residency & Fellowship

Residency, Internal Medicine, University of Rochester Medical Center. 1995 - 1997

Internship, Internal Medicine, University of Rochester Medical Center. 1994 - 1995

Education

MD | University of Pittsburgh School of Medicine. 1994

Awards

Lawrence A. Kohn Senior Teaching Fellow. 2024 - 2025

Murphy Faculty Award. 2022 - 2023

Residency Teaching Honor Roll. 2022 - 2023

Murphy Faculty Award. 2021 - 2022

Lawrence A. Kohn Senior Teaching Fellow. 2017 - 2018

Patient-and-Family-Centered Care Award. 2011 - 2012

Patient-And-Family-Centered Care Award. 2010 - 2011

Arthur W. Bauman Teaching Award. 2006 - 2007

Lawrence A. Kohn Senior Teaching Fellow. 2002 - 2004

Publications

Journal Articles

Training Medical Student Counselors for the Rochester Model, a Hospital Tobacco Treatment Program.

Grable JC, Shan K, Wang M, Han DD, Sportiello K, Chang M, Sysol JR, Bugbee D, Peltzer K

Journal of multidisciplinary healthcare.. 2024 17 :601-607. Epub 02/07/2024.

Integrating Tobacco Dependence Treatment into Hospital Practice using the Rochester Model

Grable, J.; Lin J.; Peltzer K.;Schultz R.; Bugbee D.; Pilpenko M.; Levy S.; Hawkins S.

Journal of Multidisciplinary Healthcare. 2023; 16: 905-911.

Health Care Workers' Knowledge, Attitudes and Practices on Tobacco Use in Economically Disadvantaged Dominican Republic Communities

Prucha, M.; Fisher, S.; Mcintosh, S.; Grable, J.; Holderness, H.; Thevenet-Morrison, K., Quinones de Monegro, Z.; Sanchez, J; Bautista, A.; Diaz, S. and Ossip, D.

Int. J. Environ. Res. Public Health 2015, 12, 4060-4075. 2015; .

Smoking cessation from office to bedside. An evidence-based, practical approach.

Grable JC, Ternullo S

Postgraduate medicine.. 2003 August 114 (2):45-8, 51-4. Epub 1900 01 01.

Refinement of Eco RI endonuclease crystal structure: a revised protein chain tracing.

Kim YC, Grable JC, Love R, Greene PJ, Rosenberg JM

Science.. 1990 September 14249 (4974):1307-9. Epub 1900 01 01.

Environmentally induced conformational changes in B-type DNA: comparison of the conformation of the oligonucleotide d(TCGCGAATTCGCG) in solution and in its crystalline complex with the restriction nuclease EcoRI.

Thomas GA, Kubasek WL, Peticolas WL, Greene P, Grable J, Rosenberg JM

Biochemistry.. 1989 March 728 (5):2001-9. Epub 1900 01 01.

"Structure and Recognition Mechanism of EcoRI Endonuclease",

Rosenberg, J.M.; McClarin, J.A.; Frederick, C.A.; Wang, B.C.; Grable, J.; Boyer, H.W.; Greene, P.

Trends in Biochem. Sci. 1987; 12: 395-398.

"Structure and Recognition Mechanism of EcoRI Endonuclease",

Rosenberg, J.M.; McClarin, J.A.; Frederick, C.A.; Wang, B.C.; Grable, J.; Boyer, H.W.; Greene, P.

Science. 1987; 12: 395-398.

Structure of the DNA-Eco RI endonuclease recognition complex at 3 A resolution.

McClarin JA, Frederick CA, Wang BC, Greene P, Boyer HW, Grable J, Rosenberg JM

Science.. 1986 December 19234 (4783):1526-41. Epub 1900 01 01.

14th annual UCLA symposia. April 6-26, 1985. Abstracts.

Journal of cellular biochemistry. Supplement.. 1985 9C :101-60. Epub 1900 01 01.

"Two-fold Symmetry of Crystalline DNA-EcoRI Endonuclease Recognition Complexes"

Grable, J.; Frederick, C.A.; Samudzi, C.; jen-Jacobson, L.; Lesser, D.; Greene, P.J.; Boyer, H.W.; Itakura, K.; Rosenberg, J.M.

J. Biomolec. Struc. Dynam. 1984; 1: 1149-1160.

Kinked DNA in crystalline complex with EcoRI endonuclease.

Frederick CA, Grable J, Melia M, Samudzi C, Jen-Jacobson L, Wang BC, Greene P, Boyer HW, Rosenberg JM

Nature.. 1984 309 (5966):327-31. Epub 1900 01 01.

Coordinate ion pair formation between EcoRI endonuclease and DNA.

Jen-Jacobson L, Kurpiewski M, Lesser D, Grable J, Boyer HW, Rosenberg JM, Greene PJ

The Journal of biological chemistry.. 1983 December 10258 (23):14638-46. Epub 1900 01 01.

Books

Gene Amplification and Analysis Volume V: Restriction Endonucleases and Methylase (1987)

Chapter: "The Structure and Function of the EcoRI Restriction Endonuclease"

Biological Organization: Macromolecular Interactions at High Resolution (1987)

Chapter: "The Structure and Function of EcoRI Endonuclease"

Protein Modification and Design (1987)

Chapter: Development of Protein Design Strategy for EcoRI Endonuclease"

Ratings & Comments

At URMC, we believe that patients should be empowered to make the right decisions regarding their personal healthcare. To do so, transparency is critical. URMC partners with Press Ganey, to survey our patients about all aspects of their care experience. We are now putting this pertinent information at your fingertips by displaying star ratings for our providers along with anonymous patient comments on our website. This will help you make better-informed choices about how and with whom you seek care. Click here to learn more about the surveys used to generate this vital information. Learn more about our survey process.

Ratings

Care provider's discussion of any proposed treatment (options, risks, benefits, etc.)

4.9 stars

Likelihood of recommending this care provider to others

4.9 stars

Explanations the care provider gave you about your problem or condition

4.9 stars

Care provider's efforts to include you in decisions about your care

5.0 stars

Concern the care provider showed for your questions or worries

5.0 stars

Patient Comments

5.0 stars

Wonderful doctor. Very caring

Jan 24, 2025

5.0 stars

It was my first appointment with Dr. Grable. He was extremely thorough in learning about my historical and current health status.

Jan 23, 2025

5.0 stars

Dr. Grable is an amazing PCP.

Dec 28, 2024

5.0 stars

Dr Grable was very caring and concerned about my situation

Nov 17, 2024

5.0 stars

Excellent, as always!

Aug 28, 2024

5.0 stars

Dr. Understand what is wrong with me

Jun 28, 2024

5.0 stars

Dr.Grable is the BEST!

Mar 03, 2024

5.0 stars

Dr. Grable is very caring and concrened about my health and he responds all my questions. He also thoughorly conduct examins my health based on my health history. He is very easy to talk to and ask questions.

Dec 31, 2023

5.0 stars

Dr. Grable has been my PCP for many years. He has always listened attentively to any issues that I raised, explained any results and options throughly, and communicated extremely promptly about test results or in answering questions via MyChart. He has also been consistently very encouraging as my own self-care improved. I consider Dr Grable an outstanding physician, and have recommended him to others without reservation and with highest enthusiasm. It has been a pleasure working with him in trying to stay to healthy!

Nov 04, 2023

5.0 stars

Dr. Grable is an exceptional caring professional who is truly concerned for his patients well being.

Sep 22, 2023