Dr. Grable is Professor of Medicine at URMC. After serving in the U.S. Army, he received his Ph.D. in Biology and M.D. degree from the University of Pittsburgh. Dr. Grable then completed his Internal Medicine Residency at URMC. His duties include seeing patients as a Hospitalist, as a IM resident clinic preceptor and in private practice. He is an Assistant Program Director for the residency program and performs tobacco cessation research.

Certified Specialties

Internal Medicine - American Board of Internal Medicine

Faculty Appointments

Professor of Clinical Medicine (Part-Time) - Department of Medicine, General Medicine (SMD)

Credentials

Residency & Fellowship

Residency, Internal Medicine, University of Rochester Medical Center. 1995 - 1997

Internship, Internal Medicine, University of Rochester Medical Center. 1994 - 1995

Education

MD | University of Pittsburgh School of Medicine. 1994

Awards

Lawrence A. Kohn Senior Teaching Fellow. 2024 - 2025

Murphy Faculty Award. 2022 - 2023

Residency Teaching Honor Roll. 2022 - 2023

Murphy Faculty Award. 2021 - 2022

Lawrence A. Kohn Senior Teaching Fellow. 2017 - 2018

Patient-and-Family-Centered Care Award. 2011 - 2012

Patient-And-Family-Centered Care Award. 2010 - 2011

Arthur W. Bauman Teaching Award. 2006 - 2007

Lawrence A. Kohn Senior Teaching Fellow. 2002 - 2004

Publications

Journal Articles

Training Medical Student Counselors for the Rochester Model, a Hospital Tobacco Treatment Program.

Grable JC, Shan K, Wang M, Han DD, Sportiello K, Chang M, Sysol JR, Bugbee D, Peltzer K

Journal of multidisciplinary healthcare.. 2024 17 :601-607. Epub 02/07/2024.

Integrating Tobacco Dependence Treatment into Hospital Practice using the Rochester Model

Grable, J.; Lin J.; Peltzer K.;Schultz R.; Bugbee D.; Pilpenko M.; Levy S.; Hawkins S.

Journal of Multidisciplinary Healthcare. 2023; 16: 905-911.

Health Care Workers' Knowledge, Attitudes and Practices on Tobacco Use in Economically Disadvantaged Dominican Republic Communities

Prucha, M.; Fisher, S.; Mcintosh, S.; Grable, J.; Holderness, H.; Thevenet-Morrison, K., Quinones de Monegro, Z.; Sanchez, J; Bautista, A.; Diaz, S. and Ossip, D.

Int. J. Environ. Res. Public Health 2015, 12, 4060-4075. 2015; .

Smoking cessation from office to bedside. An evidence-based, practical approach.

Grable JC, Ternullo S

Postgraduate medicine.. 2003 August 114 (2):45-8, 51-4. Epub 1900 01 01.

Refinement of Eco RI endonuclease crystal structure: a revised protein chain tracing.

Kim YC, Grable JC, Love R, Greene PJ, Rosenberg JM

Science.. 1990 September 14249 (4974):1307-9. Epub 1900 01 01.

Environmentally induced conformational changes in B-type DNA: comparison of the conformation of the oligonucleotide d(TCGCGAATTCGCG) in solution and in its crystalline complex with the restriction nuclease EcoRI.

Thomas GA, Kubasek WL, Peticolas WL, Greene P, Grable J, Rosenberg JM

Biochemistry.. 1989 March 728 (5):2001-9. Epub 1900 01 01.

"Structure and Recognition Mechanism of EcoRI Endonuclease",

Rosenberg, J.M.; McClarin, J.A.; Frederick, C.A.; Wang, B.C.; Grable, J.; Boyer, H.W.; Greene, P.

Trends in Biochem. Sci. 1987; 12: 395-398.

"Structure and Recognition Mechanism of EcoRI Endonuclease",

Rosenberg, J.M.; McClarin, J.A.; Frederick, C.A.; Wang, B.C.; Grable, J.; Boyer, H.W.; Greene, P.

Science. 1987; 12: 395-398.

Structure of the DNA-Eco RI endonuclease recognition complex at 3 A resolution.

McClarin JA, Frederick CA, Wang BC, Greene P, Boyer HW, Grable J, Rosenberg JM

Science.. 1986 December 19234 (4783):1526-41. Epub 1900 01 01.

14th annual UCLA symposia. April 6-26, 1985. Abstracts.

Journal of cellular biochemistry. Supplement.. 1985 9C :101-60. Epub 1900 01 01.

"Two-fold Symmetry of Crystalline DNA-EcoRI Endonuclease Recognition Complexes"

Grable, J.; Frederick, C.A.; Samudzi, C.; jen-Jacobson, L.; Lesser, D.; Greene, P.J.; Boyer, H.W.; Itakura, K.; Rosenberg, J.M.

J. Biomolec. Struc. Dynam. 1984; 1: 1149-1160.

Kinked DNA in crystalline complex with EcoRI endonuclease.

Frederick CA, Grable J, Melia M, Samudzi C, Jen-Jacobson L, Wang BC, Greene P, Boyer HW, Rosenberg JM

Nature.. 1984 309 (5966):327-31. Epub 1900 01 01.

Coordinate ion pair formation between EcoRI endonuclease and DNA.

Jen-Jacobson L, Kurpiewski M, Lesser D, Grable J, Boyer HW, Rosenberg JM, Greene PJ

The Journal of biological chemistry.. 1983 December 10258 (23):14638-46. Epub 1900 01 01.

Books

Gene Amplification and Analysis Volume V: Restriction Endonucleases and Methylase (1987)

Chapter: "The Structure and Function of the EcoRI Restriction Endonuclease"

Authors: Rosenberg, J.M.; McClarin, J.A.; Frederick, C.A.; Grable, J.; Boyer, H.W.; Greene, P.

Publisher: Elsevier/North-Holland 1987

Biological Organization: Macromolecular Interactions at High Resolution (1987)

Chapter: "The Structure and Function of EcoRI Endonuclease"

Authors: Rosenberg, J.M.; McClarin, J.A.; Frederick, C.A.; Wang, B.C.; Boyer, H.W.; Grable, J.; Greene, P.

Publisher: Academic Press, Inc. 1987

Protein Modification and Design (1987)

Chapter: Development of Protein Design Strategy for EcoRI Endonuclease"

Authors: Rosenberg, J.M.; Wang, B.C.; Frederick, C.A.; Reich, N.; Boyer, H.W.; Greene, P.; Grable, J.; McClarin, J.A.

Publisher: Alan R. Liss, Inc 1987

Ratings & Comments

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Ratings

During this visit, did this provider spend enough time with you?

5.0

During this visit, did this provider show respect for what you had to say?

5.0

During this visit did this provider give you easy to understand information about these health questions or concerns?

5.0

During this visit, did this provider listen carefully to you?

5.0

During this visit, did this provider explain things in a way that was easy to understand?

5.0

Patient Comments

Excellent, as always!

Aug 28, 2024

5.0

Dr. Understand what is wrong with me

Jun 28, 2024

5.0

Dr.Grable is the BEST!

Mar 03, 2024

5.0

Dr. Grable is very caring and concrened about my health and he responds all my questions. He also thoughorly conduct examins my health based on my health history. He is very easy to talk to and ask questions.

Dec 31, 2023

5.0

Dr. Grable has been my PCP for many years. He has always listened attentively to any issues that I raised, explained any results and options throughly, and communicated extremely promptly about test results or in answering questions via MyChart. He has also been consistently very encouraging as my own self-care improved. I consider Dr Grable an outstanding physician, and have recommended him to others without reservation and with highest enthusiasm. It has been a pleasure working with him in trying to stay to healthy!

Nov 04, 2023

5.0

Dr. Grable is an exceptional caring professional who is truly concerned for his patients well being.

Sep 22, 2023

5.0

Excellent doctor. Good experience

Jul 23, 2023

5.0

Dr. John Grable discuss all the of my health concerns and offerred appropriate advise.

Jun 30, 2023

5.0

Good as ever (since 1997)

Apr 14, 2023

5.0

Dr. Grable is just the best. Listens, cares. I never feel rushed. He is amazing.

Feb 02, 2023

5.0

Went to urgent care for knee pain/sprain, then scheduled follow up with this provider via myChart. Was immediately scheduled to see NP, but got follow-up from Dr. Grable indicating he would see me later on the scheduled day, three days earlier if needed (i.e., would make time). Came at scheduled time (4:20pm) but knew appointment would likely start later b/c end of day. Dr Grable saw me at 5p and spent over 45 minutes THOROUGHLY examining my knee. He scheduled me for PT which will start today. Dr Grable has been my PCP for many years. I greatly appreciate his complete examinations and detailed explanations of cause/effect/treatment. This is the first time I have seen him on a more urgent basis.

Jan 27, 2023

5.0

You need more physicians like Dr. John Grable.

Dec 05, 2022

5.0

Dr Grable is exceptionally understanding, compassionate, courteous and thorough

Nov 21, 2022

5.0

Since this was my first visit with this provider, I had a good feeling about him and was glad he took me on as a patient. He was knowledgable and it was a good visit.

Sep 02, 2022

5.0

I was impressed that Dr Grable gave me his full attention for almost an hour. However I'm not convinced he understands [...] on Inflammation in joints and tissues.

Aug 20, 2022

5.0

Dr. Grable is the greatest gift and deserves a raise!

Jun 29, 2022

5.0

Dr. Grable was wonderful. He was very concerned about my health. He is my daughter's doctor and took me as a patient while I am in Rochester.

Apr 19, 2022