UR Medicine Faculty
The University of Rochester Medical Faculty Group
(URMFG) consists of over 900 specialist and primary care providers spanning 19
departments.
URMFG is certified by the National Committee for Quality Assurance.
Accountable Health Partner
Accountable Health Partners (AHP) is a network of
over 2,000 community and UR medical faculty and a dozen leading hospitals throughout the
region. AHP offers a full range of care.
“My goal is to educate my patients about their cancer and help them make the best choice for themselves and their family on how it should be treated. I provide the same level of care that I would give to any member of my family.”
Areas of Expertise
• Liver cancer • Pancreatic canc...
“My goal is to educate my patients about their cancer and help them make the best choice for themselves and their family on how it should be treated. I provide the same level of care that I would give to any member of my family.”
Areas of Expertise
• Liver cancer • Pancreatic cancer • Gallbladder and Bile duct cancer • Metastatic colon cancer to the liver • Gastric cancer • Gastrointestinal neuroendocrine tumors
I chose this field to treat hepatobiliary and pancreatic cancer because they are aggressive cancers that require a high degree of complex multidisciplinary oncologic management. This is challenging, but can also be very rewarding. I wanted to apply myself to this field not only to try to help patients afflicted with these cancers, but to also move the field forward through research.
In addition, I chose the field of liver surgery for several reasons. For one, I am fascinated by the liver. It is one of the most complex organs in the body both structurally and functionally and is essential for life. It is one of the most common places that cancers spread to as they progress and, it is the only organ capable of regeneration. As a surgeon, I can use this to my advantage when performing liver surgery as we have techniques to grow more liver when it is necessary to remove a very large part to treat a cancer.
Patients and providers alike can be confident knowing I have devoted the greater part of my career to the study of cancer and the treatment of it. This is due to the strong empathy I have for cancer patients and my intense passion for cancer research. I also have a Ph.D. in molecular and cell biology and have been performing cancer research for over 20 years. I am intensely curious, which drives my desire to understand what we do not know. My curiosity is also fueled by experiences in patient care, resulting in new clinical trials that I lead as well as research conducted by my laboratory.
Certified Specialties
Surgery (General Surgery)
- American Board of Surgery
Faculty Appointments
Professor
-
Department of Surgery, Oncology (SMD)
Professor
-
Department of Biomedical Genetics (SMD) - Joint
Professor
-
Cancer Center - Joint
Credentials
Residency & Fellowship
Fellowship, Surgical Oncology, Memorial Sloan-Kettering Cancer Center. 2006 - 2008
Internship, Surgery (General Surgery), Mattel Children's Hospital at UCLA Medical Center. 1997 - 1998
Education
PhD | University of California Los Angeles Medical Center.Pathology, Medical Microbiology.2003
MD | University of Illinois College of Medicine (USA).1997
Awards
Elected Membership.2019
Elected Membership.2018
Harrington Scholar Innovator Award.2013
Most Outstanding Faculty Basic Science Research Paper.2013
Sidney Kimmel Scholar Award.2012
Scientific Day Research Award.2006
Scientific Day Research Award.2005
Scholar in Training Award.2003
Resident Teaching Award.2003
Scholar in Training Award.2001
Postdoctoral Investigators.2001
Scholar in Training Award.2000
Medical Honor Society.1997
Student Abstract Prize.1994
Student Research Award.1993
Research
Gastrointestinal cancers such as pancreatic, bile duct and liver cancers are plagued by ineffective systemic therapies underscoring the tremendous unmet need for novel therapies. The Carpizo Laboratory studies cancer biology with an emphasis on developmental therapeutics. Our studies range from earl...
Gastrointestinal cancers such as pancreatic, bile duct and liver cancers are plagued by ineffective systemic therapies underscoring the tremendous unmet need for novel therapies. The Carpizo Laboratory studies cancer biology with an emphasis on developmental therapeutics. Our studies range from early drug discovery projects to translational studies of novel therapies that are about to enter or just have entered into clinical trials. These translational studies employ a variety of experimental systems including mouse cancer models, patient derived tissues as well as therapeutic clinical protocols.
Another major avenue of research in the Carpizo lab is the study of cancer metastasis and dormancy. Most solid organ cancers (i.e. breast, lung, pancreas) are treated with surgery when it appears that the disease has not spread to distant organs. This is highly effective (curative) for a number of tumor types such as breast, prostate, and thyroid cancer. However, for a number of gastrointestinal cancers such as pancreas, liver and bile duct cancer, surgery is relatively ineffective as the majority of these patients go on to suffer metastatic recurrence. This means that at the time of the surgery, they harbor disseminated tumor cells in their bodies that for a period of time after surgery remain dormant. We want to understand what the molecular mechanisms that control cancer dormancy are, what awakens these cells and how can we devise therapies that either maintain the dormant state, or drive the cells into senescence.
Dudgeon C, Casabianca A, Harris C, Ogier C, Bellina M, Fiore S, Bernet A, Ducarouoge B, Goldschneider D, Su X, Pitarresi J, Hezel A, De S, Narrow W, Soliman F, Shields C, Vendramini-Costa DB, Prela O, Wang L, Astsaturov I, Mehlen P, Carpizo DR
Cell reports.. 2023 November 2842 (11):113369. Epub 11/03/2023.
Casabianca AS, Tsagkalidis V, Burchard PR, Chacon A, Melucci A, Reitz A, Swift DA, McCook AA, Switchenko JM, Shah MM, Carpizo DR
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.. 2022 December 48 (12):2448-2454. Epub 06/22/2022.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.. 2022 December 48 (12):2570-2571. Epub 08/27/2022.
Greco SH, August DA, Shah MM, Chen C, Moore DF, Masanam M, Turner AL, Jabbour SK, Javidian P, Grandhi MS, Kennedy TJ, Alexander HR, Carpizo DR, Langan RC
Surgery open science.. 2021 January 3 :22-28. Epub 12/16/2020.
Kangas-Dick A, Gall V, Hilden P, Turner A, Greenbaum A, Sesti J, Paul S, Carpizo D, Kennedy T, Sadaria Grandhi M, Alexander HR, Wang S, Geffner S, August D, Langan RC
Surgery.. 2020 July 168 (1):49-55. Epub 05/13/2020.
Khullar K, Patel NM, Anderson C, Chundury A, Carpizo D, Feingold D, Grandhi M, Hochster H, Jani K, Kennedy T, Langan R, Spencer K, August D, Jabbour SK
Sayan M, Yegya-Raman N, Greco SH, Gui B, Zhang A, Chundury A, Grandhi MS, Hochster HS, Kennedy TJ, Langan RC, Malhotra U, Rustgi VK, Shah MM, Spencer KR, Carpizo DR, Nosher JL, Jabbour SK
Frontiers in oncology.. 2019 9 :345. Epub 06/18/2019.
Gui B, Weiner AA, Nosher J, Lu SE, Foltz GM, Hasan O, Kim SK, Gendel V, Mani NB, Carpizo DR, Saad NE, Kennedy TJ, Zuckerman DA, Olsen JR, Parikh PJ, Jabbour SK
American journal of clinical oncology.. 2018 September 41 (9):861-866. Epub 1900 01 01.
Publisher:
Blackwell Publishing, Inc., Malden, MA 2004
Ratings & Comments
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Ratings
During this visit, did this provider spend enough time with you?
4.9 stars
During this visit, did this provider show respect for what you had to say?
5.0 stars
During this visit did this provider give you easy to understand information about these health questions or concerns?
4.8 stars
During this visit, did this provider listen carefully to you?
5.0 stars
During this visit, did this provider explain things in a way that was easy to understand?
4.9 stars
Patient Comments
I felt I was with the "A" team, and would be well taken care of.
Sep 23, 2024
Excellent visit with Dr. Carpizo. He's mature and was open to my experience helping a friend go through the Whipple procedure, which was very negative for her and for me. He also understands concern of elderly facing serious illness (I'm 86). H promised a follow-up for treatment (I received call for that today). Dr. Carpizo explained function of the pancreas and showed me the CT scan I had of it several weeks ago. He increased my confidence in making a good future decision about treatment options.
Sep 03, 2024
All good
Aug 25, 2024
5.0 stars
Dr. Carpizo was thorough discussing my MRI. He answered all my concerns and questions.
Feb 26, 2024
5.0 stars
Provided detailed explanation of my condition in terms that I could easily understand - Doc Carpizo & nurse were excellent as both listened attentively to my concerns.
Feb 06, 2024
5.0 stars
Outstanding - went above & beyond to help me & even spoke to my [...] provider to do what was best for me.
Aug 22, 2023
5.0 stars
Dr. Carpizo is the first surgeon I have ever met with a good "bedside manner.
May 05, 2023
Dr Carpizo is absolutely the finest physician I have ever encountered
Feb 19, 2023
5.0 stars
Excellent bedside manner/wonderful sense of humor!
Feb 07, 2023
5.0 stars
We were very thankful for the amount of time Dr Carpizo spent with us during this visit. He listened to everything we had to say and made us feel very confident that Dr Carpizo understands this very long standing health issue and is competent to resolve it.