Immunohistochemistry
About Us
The Immunohistochemistry (IHC) Laboratory provides clinical testing on surgical and cytology specimens for proteins, enzymes and infectious agents by immunohistochemical methods. We offer immunohistochemical and in-situ hybridization staining to outside clients with interpretation by our pathologists, or we return them for interpretation to the requesting pathologist.
Our unit provides the university community with extensive knowledge on immunohistochemical testing in both clinical and research settings. Most clinical testing is performed within 24 hours, giving rapid results to pathologists for final diagnosis.
All of our stains are rigorously validated according to the latest CAP guidelines, providing test results which you can trust as the treatment plan is determined by the clinician and the patient; some examples include Estrogen and Progesterone Receptors, Her2-neu protein over-expression, and PD-L1 testing
What We Offer
Below are examples of the types of specimens on which we routinely perform IHC. You can also download our complete list of Immunohistochemical Stains
Contact Us
For questions, please contact the Immunohistochemistry Laboratory at (585) 275-7210.
| Specimen | Description | Image |
|---|---|---|
| Bone & Soft Tissue | The epithelioid component of biphasic synovial sarcoma is highlighted by cytokeratin stain. | |
| Breast | IHC confirms HER2 status in invasive breast cancer. | |
| Dermatological | Cytokeratin 7 highlights the malignant cells in Paget disease. | |
| Gastrointestinal | IgG4 immunostain highlights plasma cells in a case of autoimmune pancreatitis. | |
| Genitourinary | PIN4 multiplex stain confirms the presence of prostate cancer in small needle biopsies. | |
| Gynecological | Cervical rhabdomyosarcoma showing Myogenin expression. | |
| Thoracic (Lung) | Squamous cell carcinoma demonstrating nuclear and cytoplasmic immunoreactivity with p16. | |
| Neurological | Phosphotau immunoreactivity in neurofibrillary tangles, an IHC test for Alzheimer’s disease, variants of dementia and chronic traumatic encephalopathy. | |
| Pediatric | The immunostain p57 confirms the presence of a complete hydatiform mole. |