Kate G. Ackerman, M.D., M.B.A.
| Associate Professor, Pediatrics
Research Interest:
Congenital Diaphragmatic Hernia.
Assistant Professor, Biomedical Genetics
Research Interest:
Role of Circadian Rhythm in in gene regulation and cancer cell biology and metabolism.
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Assistant Professor - Department of Medicine , Aab Cardiovascular Research Institute (SMD)
Assistant Professor - Department of Pharmacology and Physiology (SMD)
Research Interest:
LncRNA control of heart development and disease; Discovery and function of micropeptides encoded by putative lncRNAs; Genome-editing by RNA-guided nucleases.
| Assistant Professor | Lab Website
Research Interest:
Role of cancer stem cell interactions with their microenvironment in disease progression.
| Assistant Professor | Visit Lab Website
Research Interest:
Investigating cell division and adhesion in epithelial tissues, with a particular interest in how tissue integrity is established and maintained during development.
Professor - Department of Medicine , Cardiology
Professor - Department of Neurology
Professor - Department of Pharmacology and Physiology
Distinguished University Professor - President's Office (UR)
Research Interest:
Signaling transduction mechanisms in the vascular system.
| Professor, Biomedical Genetics
Research Interest:
Genetics of transcription factors and their role in aging and disease.
Professor - Department of Microbiology and Immunology (SMD)
Albert and Phyllis Ritterson Professorship - Department of Microbiology and Immunology (SMD)
Associate Vice President for Health Sciences Research - Office of Sr VP for Research (UR)
Vice Dean for Research, SMD - Dean's Office M&D - Administration (SMD)
Research Interests:
Understanding the interaction of HIV with glial cells; Developing an improved live attenuated influenza vaccine (LAIV); Elucidating the host cell response to infection by viral pathogens (with emphasis on SARS-CoV-2 and Adeno-associated virus, AAV).
Associate Professor - Department of Biochemistry and Biophysics (SMD)
Research Interest:
Structural dynamics of the ribosome and ribosomal ligands during proteins synthesis, regulation of protein synthesis by mRNA structure in normal and diseased cells, and mechanisms of antibiotic action.
Assistant Professor, Department of Biomedical Genetics, Department of Pharmacology and Physiology
Research Interest:
The role of antioxidants in disease and the development of novel strategies to manipulate them therapeutically.
Assistant Professor, Biomedical Genetics
Research Interests:
Molecular development of the eye and inner ear; anterior segment dysgenesis (ASD) and developmental glaucoma; congenital deafness and vestibular dysfunction.
- Associate Professor - Department of Biochemistry and Biophysics (SMD)
- Research Interests:
Investigation of the germ cell genome, the only genome carrying the duty of integrating new information with genetic history, enabling reproduction and evolution—the key difference between life and non-life.
Research Interest:
Neurobiology of glaucoma, molecular processes that lead to retinal ganglion cell death.
Associate Professor, Department of Orthopaedics , Department of Biomedical Engineering, Department of Pathology and Laboratory Medicine |
Research Interest:
Musculoskeletal tissue regeneration.
Sanjay B. Maggirwar, M.B.A., Ph.D.
Associate Professor, Biochemistry & Biophysics
Research Interest:
The molecular basis of human diseases, including but not limited to the most common single-gene cause of intellectual disability and autism, Fragile X Syndrome, and the development of therapeutics.
Professor - Department of Pediatrics , Neonatology
David H. Smith Professor in Pediatrics - Department of Pediatrics
Professor (Part-Time) - Department of Environmental Medicine
Professor - Department of Biomedical Genetics
Research Interest:
Genetic mechanisms of susceptibility to congenital and infectious lung diseases, focusing on developmental antecedents and the influence of environmental factors.
Professor, Biomedical Genetics, Neuroscience
Research Interest:
Identification of different stem and precursor cell pools in CNS that may be critical for cell replacement therapies or are targets of insults that lead to developmental pathologies.
Assistant Professor, Biomedical Genetics
Research Interests:
tRNA biogenesis, function and quality control; intellectual disability due to deficiencies.
Research Interest:
Our research program focuses on mechanisms underlying gene environment interaction in pregnancy. We are interested in elucidating how environmental factors influence epigenetic regulation of developmental-relevant genes including imprinted genes, and how exposure modulates maternal-fetal health.
| Adjunct Professor - Department of Medicine , Aab Cardiovascular Research Institute (SMD)
Professor, Department of Medicine , Department of Pharmacology and Physiology
Research Interest:
Integrative Physiology.
| Professor, Biomedical Genetics
Research Interests:
Discovering new treatments for afflictions that lack satisfactory therapies, and to better understand the toxicity of currently used medicines; studies span normal and pathological cell function, with focus on stem and progenitor cells.
| Professor, Pediatrics
Research Interest:
Effects of newborn hypoxia on lung and heart development.
Professor - Department of Biomedical Genetics (SMD)
Interim Director, Oral & Craniofacial Biology - Department of Dentistry (SMD)
Research Interest:
Protective and regenerative strategies for salivary gland function and radiation therapies.
Alexander R. Paciorkowski, M.D.
| Associate Professor - Department of Biomedical Genetics
Research Interests:
tRNA biogenesis, function and quality control; intellectual disability due to deficiencies in tRNA modifications.
Associate Professor, Department of Medicine , Department of Biochemistry and Biophysics
Research Interest:
Pathophysiological function and molecular mechanism of new non-coding RNAs (and RBPs) and new modes of gene regulation in cardiac system and cardiovascular disease.
Professor - Department of Biochemistry and Biophysics (SMD)
Research Interest:
tRNA biogenesis, function and quality control; intellectual disability due to deficiencies in tRNA modifications.
| Associate Professor, Biomedical Genetics
Research Interest:
Defining roles of glial progenitor cells and astrocytes as critical modulators in responses to chemical exposure, injury, or stress; discovering how exogenous factors contribute to neurodegenerative diseases; and developing new approaches to treat traumatic injury and neurodegenerative diseases.
Professor - Department of Microbiology and Immunology, Interim Chair Department of Microbiology and Immunology, Professor - Department of Environmental Medicine Vice Chair - Department of Microbiology and Immunology |
Research Interest:
Experimental platform using the amphibian Xenopus for research in immunotoxicology, fundamental and medical immunology.
Marlies P. Rossmann, M.D., Ph.D.
- Assistant Professor - Department of Biomedical Genetics (SMD)
Research Interest: Elucidate the metabolic origins of a variety of diseases, facilitate novel metabolism-centered differentiation therapies for hematological malignancies, and combat the decline in lymphoid cell production by the aging hematopoietic system.
Regina K. Rowe, M.D., Ph.D.
| Visit Rowe Lab
- Assistant Professor - Department of Pediatrics , Infectious Diseases (SMD)
Research Interest:
Mechanisms of how allergic inflammation impacts innate immune cell antiviral responses.
| Assistant Professor, Biomedical Genetics
Research Interest:
Aging at the Genetic, Molecular and Organismal Level.
Professor - Department of Orthopaedics , Center for Musculoskeletal Research
Director - Center for Musculoskeletal Research
Richard and Margaret Burton Distinguished Professor in Orthopaedics - Department of Orthopaedics
Professor - Department of Urology
Professor - Department of Medicine , Allergy/Immunology and Rheumatology
Professor - Department of Pathology and Laboratory Medicine
Professor - Department of Microbiology and Immunology
Professor - Department of Biomedical Engineering
Research Interest:
Inflammatory bone loss as seen in rheumatoid arthritis, infections, tumor metastasis and wear debris induced osteolysis around prosthetic implants.
| Assistant Professor, Ophthalmology
Research Interest:
Cellular and molecular mechanisms of retinal and neurodegenerative diseases in patient-derived induced pluripotent stem cell (iPSC) model systems.
| Associate Professor, Medicine, Pharmacology & Physiology, Biomedical Engineering
Research Interest:
Cellular and molecular mechanisms of heart development, disease, and regeneration; Transcriptional regulation of fibroblast plasticity and cardiac fibrosis.
| Professor (Part-Time) - Department of Biochemistry and Biophysics
Associate Professor - Department of Pediatrics , Neonatology
Research Interest:
Understanding how regulation of RNA Polymerase II activity regulates cellular differentiation, with a focus on erythropoiesis. Delineating epigenetic control of normal erythropoiesis; determining the contribution of disrupted epigenetic regulation to inherited anemias.
Assistant Professor, Department of Ophthalmology, Department of Neuroscience, Center for Visual Science A&S (RC)
Research Interest:
Signaling mechanisms linking neuronal activity and gene expression.
Associate Professor - Department of Microbiology and Immunology
Associate Professor - Department of Biostatistics and Computational Biology
Associate Professor - Department of Biomedical Genetics
Research Interest:
Signaling mechanisms linking neuronal activity and gene expression.
Professor, Department of Neurology, Saunders Family Distinguished Professor in Neuromuscular Research - Department of Neurology (SMD), Department of Neuroscience
Research Interests:
Neurogenetics, experimental therapeutics, repeat expansion diseases.