Woeller Lab
Welcome to the Woeller Lab
We are interested in the molecular and cellular pathways that drive the response to injury of the eye and surrounding tissue. Whether autoimmune, chemical or physical insult, the response to injury includes inflammation and activation of specialized cells that support normal wound healing. The response of these cells can sometimes proceed out of control causing debilitating tissue damage, pain, vision impairment and blindness. Our laboratory studies why and how these cells respond to injury with the goal of developing novel, targeted treatments that can prevent and/or resolve tissue damage and vision loss.
Collynn Woeller, Ph.D.
Principal Investigator
Research Projects
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Publications
View All Publications- Tapinarof, an Aryl Hydrocarbon Receptor Ligand, Mitigates Fibroblast Activation in Thyroid Eye Disease: Implications for Novel Therapy.; Investigative ophthalmology & visual science; Vol 65(13), pp. 40. 2024 Nov 04.
- PPARγ drives mitochondrial stress signaling and the loss of atrial cardiomyocytes in newborn mice exposed to hyperoxia.; Redox biology; Vol 76, pp. 103351. 2024 Sep 12.
- Staphylococcal Enterotoxins Promote Virulence in Bacterial Keratitis.; Investigative ophthalmology & visual science; Vol 64(5), pp. 5. 2023 May 01.
- TNF-α and NF-κB signaling play a critical role in cigarette smoke-induced epithelial-mesenchymal transition of retinal pigment epithelial cells in proliferative vitreoretinopathy.; PloS one; Vol 17(9), pp. e0271950. 2022 Sep 01.
Contact Us
Woeller Lab
601 Elmwood Ave
Rochester, NY 14642