Research Networks
Our participation in Pediatric Critical Care research networks allows our faculty to collaborate with teams of investigators in multi-center studies on a national and an international level.
- Pediatric CDS Collaborative: A grassroots collaborative of pediatric clinician scientists aimed at understanding and improving clinical decision support tools. Funded by an NCATS UG3/UH3, this group is building a framework for shared development and assessment of CDS.
- PICU Data Collaborative: A 19-member organization committed to the development of the largest granular clinical dataset of critically ill children. Supported by the Virtual PICU at CHLA, this organization (of which Rochester is a founding member, site PI Dziorny) has developed, harmonized, and is beginning to utilize a cloud-based dataset of >150,000 critical care admissions for applications such as machine learning development and comparative effectiveness research.
- Pediatric Cardiac Care Consortium PC4: The Pediatric Cardiac Critical Care Consortium (PC⁴) aims to improve the quality of care to patients with critical pediatric and congenital cardiovascular disease. It is a collaborative of over 70 hospitals that participate in the care of critically ill patients with pediatric and congenital heart disease. Using a continuously updated data infrastructure, multi-institutional quality improvement and research projects, and a transparent collaborative learning process, it allows partnership between institutions to improve the care of these precious and fragile patients
- Pediatric Acute Lung Injury and Sepsis Investigators (PALISI): The PALISI Network specializes in identifying preventive, therapeutic, and preventive strategies for acute respiratory distress syndrome, sepsis, multi-organ failure, and other acute, life-threatening pulmonary or systemic inflammatory syndromes that affect infants and children. Funded by subscriptions from members who now comprise a multidisciplinary group of investigators from over 90 PICUs all over the United States (US) and Canada, with collaborations across the globe.
The network approach in each field follows, where necessary, the full spectrum of clinical and translational research, including: immunobiology studies for understanding basic pathologic mechanisms; surveys to explore contemporary clinical practice; consensus conferences to establish agreement about literature evidence; observational prevalence and incidence studies to measure scale of a clinical issue or question; case control studies as preliminary best evidence for design of definitive prospective studies; and, randomized controlled trials for informing clinical care.
- BloodNet: BloodNet, the Pediatric Critical Care Blood Research Network, is a subgroup of PALISI. This international network of over 160 members from 11 countries (Argentina, Australia, Belgium, Canada, Ecuador, Italy, Israel, Spain, The Netherlands, the United Kingdom, and the USA) has a mission to improve outcomes in critically ill children by supporting and performing research in transfusion medicine, immunology, hemostasis, and blood management.
- Virtual PICU (VPS): Supports PICU’s around the world to gather granular data elements about populations cared for in pediatric intensive care units. Unit sizes range from 4-72 PICU beds along with a variety of different unit models ranging from 24-hour In-House Attending Coverage to Units with Separate Intermediate ICUs. Numerous drill down opportunities based on PICU characteristics are available including, but are not limited to, Neuro Critical Care (“NCC”), Pediatric Trauma Assessment and Management (“PTAM”) and others.