Cancer Microenvironment
The Cancer Microenvironment (CM) research program leverages expertise in immunology, stem cell biology, radiobiology, and nanotechnology, to investigate how the tumor microenvironment impacts the way cancer arises, progresses, and responds to therapy. Collaboration is essential, and program members are particularly focused on translational research that impacts myeloid and lymphoid malignancies and pancreatic cancer.
The specific aims of the CM program are:
- To disrupt and reprogram cancer-promoting microenvironments.
- To restore normal tissue homeostasis from cancer and cancer treatment-induced injury.
The goals of this high-impact basic science program complement the work done at Wilmot’s Genetics, Epigenetics, and Metabolism (GEM) research program, and its Cancer Prevention and Control (CPC) program, and involves collaboration with the Community Outreach and Engagement (COE) office to meet the needs of Wilmot’s 27-county catchment area.
Program Leaders
Minsoo Kim, Ph.D.
Dean’s Professor of Microbiology and Immunology
Director of the Tumor Immunotherapy Research Program at Wilmot
Dr. Kim investigates innate and adaptive immune responses and cancer treatment.
Laura Calvi, M.D.,
Professor of Medicine, Neurosurgery, and Pharmacology and Physiology
Dr. Calvi is focused on bridging bone and stem cell biology to discover the regulatory components of the bone marrow microenvironment, to identify targeted therapies.
Members
Omar Aljitawi
Professor, Emergency Medicine
Paul Barr, M.D.
Assistant Professor, Medicine/Hematology Oncology
Ed Brown, Ph.D.
Associate Professor, Biomedical Engineering
Walther Richard Burack, M.D., Ph.D.
Professor, Pathology and Laboratory Medicine
Marvin Doyley, Ph.D.
Professor, Electrical and Computer Engineering
Nebojsa Duric, Ph.D.
Professor, Imaging Sciences
Jamie Flerlage, M.D., M.S.
Associate Professor, Pediatrics/Hematology Oncology
Jonathan Friedberg, M.D., M.M.Sc.
Professor, Medicine/Hematology Oncology
Benjamin Frisch, Ph.D.
Assistant Professor, Pathology and Laboratory Medicine
Scott Gerber, Ph.D.
Associate Professor, Surgery/Research
Michael Giacomelli, Ph.D.
Associate Professor, Biomedical Engineering
Angela Glading, Ph.D.
Associate Professor, Pharmacology and Physiology
Paige Lawrence, Ph.D.
Professor, Environmental Medicine
Yi-Fen Lee, Ph.D.
Professor, Urology
Jane Liesveld, M.D.
Professor, Medicine/Hematology Oncology
Brian Marples, Ph.D.
Professor, Radiation Oncology
James McGrath, Ph.D.
Associate Professor, Public Health Services
Mohammad Mehrmohammadi, Ph.D.
Associate Professor, Imaging Sciences
Richard Moore, M.D.
Professor, Obstetrics and Gynecology
Kerry O'Banion, M.D., Ph.D.
Professor, Neurology
James Palis, M.D.
Professor, Pediatrics/Hematology Oncology
Phillip Rappold, M.D., Ph.D.
Assistant Professor, Urology
Deepak Sahasrabudhe, M.D.
Professor, Medicine/Hematology Oncology
Laurie Steiner, M.D.
Associate Professor, Medicine/Hematology Oncology
Rachael Turner, M.D., Ph.D.
Assistant Professor, Medicine/Hematology Oncology
Zhenqiang Yao, B.Med., Ph.D.
Associate Professor, Pathology and Laboratory Medicine
Shu-Chi Yeh, Ph.D.
Assistant Professor, Orthopaedics
Clive Zent, M.D.
Professor, Medicine/Hematology Oncology
Xinping Zhang, B.Med., Ph.D.
Associate Professor, Orthopaedics