Flaum Eye Institute / Research / Labs / Woeller Lab / Publications

Recent Publications

1. Patrick CC
2. Roztocil E
3. Husain F
4. Feldon SE
5. Woeller CF
Tapinarof, an Aryl Hydrocarbon Receptor Ligand, Mitigates Fibroblast Activation in Thyroid Eye Disease: Implications for Novel Therapy.; Investigative ophthalmology & visual science; Vol 65(13), pp. 40. 2024 Nov 04.
1. Cohen ED
2. Roethlin K
3. Yee M
4. Woeller CF
5. Brookes PS
6. Porter GA
7. O'Reilly MA
PPARγ drives mitochondrial stress signaling and the loss of atrial cardiomyocytes in newborn mice exposed to hyperoxia.; Redox biology; Vol 76, pp. 103351. 2024 Sep 12.
1. Johnson WL
2. Sohn M
3. Woeller CF
4. Wozniak RAF
Staphylococcal Enterotoxins Promote Virulence in Bacterial Keratitis.; Investigative ophthalmology & visual science; Vol 64(5), pp. 5. 2023 May 01.
1. Wang V
2. Heffer A
3. Roztocil E
4. Feldon SE
5. Libby RT
6. Woeller CF
7. Kuriyan AE
TNF-α and NF-κB signaling play a critical role in cigarette smoke-induced epithelial-mesenchymal transition of retinal pigment epithelial cells in proliferative vitreoretinopathy.; PloS one; Vol 17(9), pp. e0271950. 2022 Sep 01.
1. Bell TJ
2. Nagel DJ
3. Woeller CF
4. Kottmann RM
Ogerin mediated inhibition of TGF-β(1) induced myofibroblast differentiation is potentiated by acidic pH.; PloS one; Vol 17(7), pp. e0271608. 2022 Jul 28.
1. Shahlaee A
2. Woeller CF
3. Philp NJ
4. Kuriyan AE
Translational and clinical advancements in management of proliferative vitreoretinopathy.; Current opinion in ophthalmology. 2022 Feb 25.
1. Rackow AR
2. Judge JL
3. Woller CF
4. Sime PJ
5. Kottmann RM
miR-338-3p Blocks TGFβ-Induced Myofibroblast Differentiation through the Induction of PTEN.; American journal of physiology. Lung cellular and molecular physiology. 2022 Jan 05.
1. Hammond CL
2. Roztocil E
3. Gupta V
4. Feldon SE
5. Woeller CF
More than Meets the Eye: The Aryl Hydrocarbon Receptor is an Environmental Sensor, Physiological Regulator and a Therapeutic Target in Ocular Disease.; Frontiers in toxicology; Vol 4. 2022.
1. Gupta V
2. Hammond CL
3. Roztocil E
4. Gonzalez MO
5. Feldon SE
6. Woeller CF
Thinking inside the box: Current insights into targeting orbital tissue remodeling and inflammation in thyroid eye disease.; Survey of ophthalmology. 2021 Sep 03.
1. Burke RM
2. Dirkx RA
3. Quijada P
4. Lighthouse JK
5. Mohan A
6. O'Brien M
7. Wojciechowski W
8. Woeller C
9. Phipps RP
10. Alexis JD
11. Ashton J
12. Small EM
Prevention of Fibrosis and Pathological Cardiac Remodeling by Salinomycin.; Circulation research. 2021 Apr 07.
1. Woeller CF
2. Lim SA
3. Roztocil E
4. Yee M
5. Beier EE
6. Puzas JE
7. O'Reilly MA
Neonatal hyperoxia impairs adipogenesis of bone marrow-derived mesenchymal stem cells and fat accumulation in adult mice.; Free radical biology & medicine. 2021 Mar 20.
1. Hammond CL
2. Roztocil E
3. Gonzalez MO
4. Feldon SE
5. Woeller CF
MicroRNA-130a Is Elevated in Thyroid Eye Disease and Increases Lipid Accumulation in Fibroblasts Through the Suppression of AMPK.; Investigative ophthalmology & visual science; Vol 62(1). 2021 Jan 04.
1. Heffer A
2. Wang V
3. Sridhar J
4. Feldon SE
5. Libby RT
6. Woeller CF
7. Kuriyan AE
A Mouse Model of Proliferative Vitreoretinopathy Induced by Intravitreal Injection of Gas and RPE Cells.; Translational vision science & technology; Vol 9(7). 2020 Jun.
1. Roztocil E
2. Hammond CL
3. Gonzalez MO
4. Feldon SE
5. Woeller CF
The aryl hydrocarbon receptor pathway controls matrix metalloproteinase-1 and collagen levels in human orbital fibroblasts.; Scientific reports; Vol 10(1). 2020 May 21.
1. Heffer AM
2. Wang V
3. Libby RT
4. Feldon SE
5. Woeller CF
6. Kuriyan AE
Salinomycin inhibits proliferative vitreoretinopathy formation in a mouse model.; PloS one; Vol 15(12). 2020.
1. Woeller CF
2. O'Reilly MA
Out-of-Tune: Fibroblasts Turn Fibrotic When They Lack a FENDRR.; American journal of respiratory cell and molecular biology. 2019 Dec 05.
1. Smith MR
2. Woeller CF
3. Uppal K
4. Thatcher TH
5. Walker DI
6. Hopke PK
7. Rohrbeck P
8. Mallon TM
9. Krahl PL
10. Utell MJ
11. Go YM
12. Jones DP
Associations of Benzo(ghi)perylene and Heptachlorodibenzo-p-dioxin in Serum of Service Personnel Deployed to Balad, Iraq, and Bagram, Afghanistan Correlates With Perturbed Amino Acid Metabolism in Human Lung Fibroblasts.; Journal of occupational and environmental medicine; Vol 61 Suppl 12. 2019 Dec.
1. Thatcher TH
2. Woeller CF
3. Thakar J
4. Khan A
5. Hopke PK
6. Smith MR
7. Uppal K
8. Walker DI
9. Go YM
10. Jones DP
11. Krahl PL
12. Mallon TM
13. Sime PJ
14. Phipps RP
15. Utell MJ
Analysis of Postdeployment Serum Samples Identifies Potential Biomarkers of Exposure to Burn Pits and Other Environmental Hazards.; Journal of occupational and environmental medicine; Vol 61 Suppl 12. 2019 Dec.
1. Khan A
2. Thatcher TH
3. Woeller CF
4. Sime PJ
5. Phipps RP
6. Hopke PK
7. Utell MJ
8. Krahl PL
9. Mallon TM
10. Thakar J
Machine Learning Approach for Predicting Past Environmental Exposures From Molecular Profiling of Post-Exposure Human Serum Samples.; Journal of occupational and environmental medicine; Vol 61 Suppl 12. 2019 Dec.
1. Thakar J
2. Thatcher TH
3. Smith MR
4. Woeller CF
5. Walker DI
6. Utell MJ
7. Hopke PK
8. Mallon TM
9. Krahl PL
10. Rohrbeck P
11. Go YM
12. Jones DP
13. Uppal K
Integrative Network Analysis Linking Clinical Outcomes With Environmental Exposures and Molecular Variations in Service Personnel Deployed to Balad and Bagram.; Journal of occupational and environmental medicine; Vol 61 Suppl 12. 2019 Dec.
1. Woeller CF
2. Thatcher TH
3. Thakar J
4. Cornwell A
5. Smith MR
6. Jones DP
7. Hopke PK
8. Sime PJ
9. Krahl P
10. Mallon TM
11. Phipps RP
12. Utell MJ
Exposure to Heptachlorodibenzo-p-dioxin (HpCDD) Regulates microRNA Expression in Human Lung Fibroblasts.; Journal of occupational and environmental medicine; Vol 61 Suppl 12. 2019 Dec.
1. Krahl PL
2. Benchoff E
3. Go YM
4. Jones DP
5. Smith MR
6. Walker DI
7. Uppal K
8. Woeller CF
9. Thatcher TH
10. Thakar J
11. Phipps RP
12. Hopke P
13. Utell MJ
14. Mallon TM
Advances in Comprehensive Exposure Assessment: Opportunities for the US Military.; Journal of occupational and environmental medicine; Vol 61 Suppl 12. 2019 Dec.
1. Mallon TM
2. Krahl PK
3. Haines KM
4. Walker DI
5. Thatcher T
6. Woeller CF
7. Thakar J
8. Hopke PK
9. Gaydos JC
10. Smith MR
11. Uppal K
12. Go YM
13. Jones DP
14. Utell M
Use of Biomarkers to Assess Environmental Exposures and Health Outcomes in Deployed Troops.; Journal of occupational and environmental medicine; Vol 61 Suppl 12. 2019 Dec.
1. Woeller CF
2. Roztocil E
3. Hammond C
4. Feldon SE
TSHR Signaling Stimulates Proliferation Through PI3K/Akt and Induction of miR-146a and miR-155 in Thyroid Eye Disease Orbital Fibroblasts.; Investigative ophthalmology & visual science; Vol 60(13). 2019 Oct 01.
1. Park RH
2. Pollock SJ
3. Phipps RP
4. Langstein HN
5. Woeller CF
Discovery of Novel Small Molecules that Block Myofibroblast Formation: Implications for Capsular Contracture Treatment.; Plastic and reconstructive surgery. Global open; Vol 7(9). 2019 Sep.
1. Thatcher TH
2. Woeller CF
3. McCarthy CE
4. Sime PJ
Quenching the fires: Pro-resolving mediators, air pollution, and smoking.; Pharmacology & therapeutics. 2019 Feb 10.
1. Heffer AM
2. Proaño J
3. Roztocil E
4. Phipps RP
5. Feldon SE
6. Huxlin KR
7. Sime PJ
8. Libby RT
9. Woeller CF
10. Kuriyan AE
The polyether ionophore salinomycin targets multiple cellular pathways to block proliferative vitreoretinopathy pathology.; PloS one; Vol 14(9). 2019.
1. Hammond CL
2. Roztocil E
3. Phipps RP
4. Feldon SE
5. Woeller CF
Proton pump inhibitors attenuate myofibroblast formation associated with thyroid eye disease through the aryl hydrocarbon receptor.; PloS one; Vol 14(9). 2019.
1. Flores EM
2. Woeller CF
3. Falsetta ML
4. Susiarjo M
5. Phipps RP
Thy1 (CD90) expression is regulated by DNA methylation during adipogenesis.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2018 Oct 30.
1. Kim N
2. Lannan KL
3. Thatcher TH
4. Pollock SJ
5. Woeller CF
6. Phipps RP
Lipoxin B4 Enhances Human Memory B Cell Antibody Production via Upregulating Cyclooxygenase-2 Expression.; Journal of immunology (Baltimore, Md. : 1950). 2018 Oct 22.
1. Lacy SH
2. Woeller CF
3. Thatcher TH
4. Pollock SJ
5. Small EM
6. Sime PJ
7. Phipps RP
Activated Human Lung Fibroblasts Produce Extracellular Vesicles with Anti-Fibrotic Prostaglandins.; American journal of respiratory cell and molecular biology. 2018 Sep 28.
1. Paine A
2. Woeller CF
3. Zhang H
4. de la Luz Garcia-Hernandez M
5. Huertas N
6. Xing L
7. Phipps RP
8. Ritchlin CT
Thy1 is a positive regulator of osteoblast differentiation and modulates bone homeostasis in obese mice.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology; Vol 32(6). 2018 Jun.
1. Falsetta ML
2. Foster DC
3. Woeller CF
4. Pollock SJ
5. Bonham AD
6. Piekna-Przybylska D
7. Maggirwar SB
8. Haidaris CG
9. Phipps RP
Toll-Like Receptor Signaling Contributes to Proinflammatory Mediator Production in Localized Provoked Vulvodynia.; Journal of lower genital tract disease; Vol 22(1). 2018 Jan.
1. Woeller CF
2. Woodroof A
3. Lacy SH
4. Cottler PS
5. Gui JL
6. Piñeros-Fernandez A
7. Pollock SJ
8. Phipps RP
Evaluating a Variable Porosity Wound Dressing With Anti-Scar Properties in a Porcine Model of Wound Healing.; Eplasty; Vol 18. 2018.
1. Woeller CF
2. Woodroof A
3. Cottler PS
4. Pollock SJ
5. Haidaris CG
6. Phipps RP
In Vitro Characterization of Variable Porosity Wound Dressing With Anti-Scar Properties.; Eplasty; Vol 18. 2018.
1. Lacy SH
2. Epa AP
3. Pollock SJ
4. Woeller CF
5. Thatcher TH
6. Phipps RP
7. Sime PJ
Activated human T lymphocytes inhibit TGFβ-induced fibroblast to myofibroblast differentiation via prostaglandins D2 and E2.; American journal of physiology. Lung cellular and molecular physiology. 2017 Dec 20.
1. Hansen TC
2. Woeller CF
3. Lacy SH
4. Koltz PF
5. Langstein HN
6. Phipps RP
Thy1 (CD90) Expression Is Elevated in Radiation-Induced Periprosthetic Capsular Contracture: Implication for Novel Therapeutics.; Plastic and reconstructive surgery; Vol 140(2). 2017 Aug.
1. Woeller CF
2. Flores E
3. Pollock SJ
4. Phipps RP
Editor's Highlight: Thy1 (CD90) Expression is Reduced by the Environmental Chemical Tetrabromobisphenol-A to Promote Adipogenesis Through Induction of microRNA-103.; Toxicological sciences : an official journal of the Society of Toxicology; Vol 157(2). 2017 Jun 01.
1. Woeller CF
2. Roztocil E
3. Hammond CL
4. Feldon SE
5. Phipps RP
The Aryl Hydrocarbon Receptor and Its Ligands Inhibit Myofibroblast Formation and Activation: Implications for Thyroid Eye Disease.; The American journal of pathology; Vol 186(12). 2016 Dec.
1. Lacy SH
2. Woeller CF
3. Thatcher TH
4. Maddipati KR
5. Honn KV
6. Sime PJ
7. Phipps RP
Human lung fibroblasts produce pro-resolving peroxisome proliferator-activated receptor-gamma ligands in a cyclooxygenase-2 dependent manner.; American journal of physiology. Lung cellular and molecular physiology. 2016 Sep 9.
1. Falsetta ML
2. Foster DC
3. Woeller CF
4. Pollock SJ
5. Bonham AD
6. Haidaris CG
7. Phipps RP
A role for bradykinin signaling in chronic vulvar pain.; The journal of pain : official journal of the American Pain Society. 2016 Aug 17.
1. Woeller CF
2. Thatcher TH
3. Van Twisk D
4. Pollock SJ
5. Croasdell A
6. Hopke PK
7. Xia X
8. Thakar J
9. Sime PJ
10. Mallon TM
11. Utell MJ
12. Phipps RP
MicroRNAs as Novel Biomarkers of Deployment Status and Exposure to Polychlorinated Dibenzo-p-Dioxins/Dibenzofurans.; Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine; Vol 58(8 Suppl 1). 2016 Aug.
1. Mallon CT
2. Rohrbeck MP
3. Haines MK
4. Jones DP
5. Utell M
6. Hopke PK
7. Phipps RP
8. Walker DI
9. Thatcher T
10. Woeller CF
11. Baird CP
12. Pollard HB
13. Dalgard CL
14. Gaydos JC
Introduction to Department of Defense Research on Burn Pits, Biomarkers, and Health Outcomes Related to Deployment in Iraq and Afghanistan.; Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine; Vol 58(8 Suppl 1). 2016 Aug.
1. Woeller CF
2. Thatcher TH
3. Van Twisk D
4. Pollock SJ
5. Croasdell A
6. Kim N
7. Hopke PK
8. Xia X
9. Thakar J
10. Mallon CT
11. Utell MJ
12. Phipps RP
Detection of Serum microRNAs From Department of Defense Serum Repository: Correlation With Cotinine, Cytokine, and Polycyclic Aromatic Hydrocarbon Levels.; Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine; Vol 58(8 Suppl 1). 2016 Aug.
1. Kim N
2. Ramon S
3. Thatcher TH
4. Woeller CF
5. Sime PJ
6. Phipps RP
Specialized proresolving mediators (SPMs) inhibit human B-cell IgE production.; European journal of immunology; Vol 46(1). 2016 Jan.
1. Judge JL
2. Owens KM
3. Pollock SJ
4. Woeller CF
5. Thatcher TH
6. Williams JP
7. Phipps RP
8. Sime PJ
9. Kottmann RM
Ionizing radiation induces myofibroblast differentiation via lactate dehydrogenase.; American journal of physiology. Lung cellular and molecular physiology; Vol 309(8). 2015 Oct 15.
1. Falsetta ML
2. Foster DC
3. Woeller CF
4. Pollock SJ
5. Bonham AD
6. Haidaris CG
7. Stodgell CJ
8. Phipps RP
Identification of novel mechanisms involved in generating localized vulvodynia pain.; American journal of obstetrics and gynecology; Vol 213(1). 2015 Jul.
1. Foster DC
2. Falsetta ML
3. Woeller CF
4. Pollock SJ
5. Song K
6. Bonham A
7. Haidaris CG
8. Stodgell CJ
9. Messing SP
10. Iadarola M
11. Phipps RP
Site-specific mesenchymal control of inflammatory pain to yeast challenge in vulvodynia-afflicted and pain-free women.; Pain; Vol 156(3). 2015 Mar.
1. Woeller CF
2. O'Loughlin CW
3. Pollock SJ
4. Thatcher TH
5. Feldon SE
6. Phipps RP
Thy1 (CD90) controls adipogenesis by regulating activity of the Src family kinase, Fyn.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology; Vol 29(3). 2015 Mar.
1. Woeller CF
2. O'Loughlin CW
3. Roztocil E
4. Feldon SE
5. Phipps RP
Salinomycin and other polyether ionophores are a new class of antiscarring agent.; The Journal of biological chemistry; Vol 290(6). 2015 Feb 6.