Welcome to the Uddin Lab

Our research interests lie at the fascinating intersection of MRI physics and neuroscience. Our vision is to transform MRI technology and methodologies to enhance the diagnosis, monitoring, and treatment of various medical conditions. We strive to push the boundaries of what's possible in medical imaging, providing deeper insights into the anatomy and physiology of the brain.

• Developing Advanced MRI Methods: We focus on creating cutting-edge MRI techniques and image processing pipelines to improve the accuracy of brain imaging.
• Unraveling Neuroinflammation and Neurodegeneration: Using diffusion MRI methods and T2-based myelin water imaging, we aim to enhance diagnostic and therapeutic approaches for neuroinflammatory and neurodegenerative diseases.
• Investigating Iron-Sensitive Biomarkers: Through quantitative susceptibility mapping and relaxometry mappings, we identify iron-sensitive measures that could serve as promising biomarkers for neurodegenerative processes in the brain.
• Probing Vascular Dysfunction: Utilizing advanced MRI techniques such as perfusion MRI and resting-state fMRI-based cerebrovascular reactivity, we explore vascular dysfunction. We are also developing an automated AI-based approach for segmenting and classifying brain arteries using time-of-flight MR Angiography, aiming to extract essential vascular features.
• Exploring Brain-Cognition Relationships: We study the relationship between structural and functional MRI measures, blood markers, and cognitive performance in diverse populations, including healthy individuals, aging populations, and those affected by neurological conditions.

Our studies encompass diverse populations, ranging from healthy individuals to aging individuals and those affected by neurological conditions such as HIV, COVID-19, CSVD, and Multiple Sclerosis.